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Step 1 > Test 71 > Flashcards

Test 71 Flashcards

1
Q

46 xx genotype

A

COMPLETE ROLE
ovum loses its maternal chromosomes and then becomes fertilized by a haploid sperm> duplication of the paternal genetic component> 46 XX

size greater than dates
high BCG levels

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2
Q

synringomyelia

A

bilateral loss of P/T

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3
Q

HIgh intraplaque activity of what enzyme can predispose a pt to MI?

A

plaque stability depends on mechanical strenght of overlying fibrous cap

inflam mphages in the intimacan reduce plaque stability by secreting metalloproteinases which degrade collagin!

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4
Q

Ventromedial hypo nuclei

A

satiety center
regulates food INTAKE

lesion> hyperphagia/aggressive behavior

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5
Q

Lateral nuclei

A

hunger

lesion> lose desire to eat

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6
Q

decreases LDL

A

statins

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7
Q

decrease TGs

A

Fibrates:
gemifibrozil
fenofibrate

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8
Q

increase HDL

A

Niacin

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9
Q

Common cause of secondary hyperPTH

A

chronic renal failure

HIGH PTH
low Ca
high phosphate
low calcitriol

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10
Q

calcitriol

A

increases Ca and pohosphate absorption> chronic renal disease> decreased calcitriol>
decrsaed Ca absorption and increased Ca loss in the urine

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11
Q

presents as gross hematuria in an elderly man

A

transitional cell carcinoma

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12
Q

RF for developing transitional cell carcinoma

A 
smoking
exposure to rubber 
plastics
aromatic amine containing dyes
textiles
lether
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13
Q

ETEC

A

produces heat labile (LT, choleragen like) and heat stable (ST) enterotoxins

LT>
actiavte AC>
incrased cAMP

ST> GC> increased cGMP

watery diarrhea

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14
Q

CSF from third to fourth ventricle

A

cerebral aqueduct

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15
Q

obstrutction foramen of monro

A

enlargement of lateral ventricle

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16
Q

obstruction of magendie and luschka

A

enlargement of all 4 ventricles

17
Q

phase 0 depolarization

A

inward flux of Ca

18
Q

transmural ischemia of hte inferior wall of the left ventricle> ST elevation in leads II, III, aVF and sinus node dysfxn

A

RCA

19
Q

anteroseptal transmural ischemia

ST elevations in V1-V4

A

LAD

20
Q

transmural ischemia of lateral wall of the ventricle w/ ST eleevations in V5, V6 and possibly I and aVL

A

LCX

21
Q

Thiopental

A

short acting barbituate used for induction anesthesia

after equilibration with the brain it rapidly redistributres into skeletal muscles nad adipose tissue

22
Q

excessive matrix metalloproteinase activity and myofibroblast accumulation in the wound margins

A

contracture>
deformities of wound and surrounding tissues

*palms, soles, anterior thorax, serious burn sites

23
Q

35 y/o M
nontender cervical lymphadenopathy
aggregates of packed follicles that obscure normal LN architecture

A

follicular lymphoa

24
Q

translocation associated w/ follicular lymphoma

A

t(14;18)

overexpression of antiapoptotic gene product, BCL-2

25
Q

BCR-ABL rearrganement t(9;22)

myeloproliferative!!

A

CML–> constituively active protein tyrosine kinase

26
Q

overexpresion of n-MYC protooncogene

A

neuroblastoma

SCC of lung

27
Q

hydrocephalus
intracranial calcifications
chorioretinitis

A

congenital toxoplasmosis

28
Q

small cardiac valvular vegetations on either side of valve resulting in fibrotic valve thickening and deformity

A

Libman Sacks endocarditis

occurs in up to 25% of pts w/ sLE

29
Q

tx of choice for uncomplicated malaria

A

chloroquine

30
Q

added to chloroquine tx for malaria to tx intrahepatic stages of malarial species

A

primaquine

p. vivax
p. ovale

31
Q

diuretic that cuases hyponatremia and hypercalcemia

A

thiazides

32
Q

diuretic that causes hypOcalcemia

A

loops

33
Q

helpful in early identification of onset of DIC in high risk pts

A

fibrinogen and platelet count

LOW fibrinogen
thrombocytopenia

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