7- Stress and Aging Flashcards Preview

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Flashcards in 7- Stress and Aging Deck (34):

What is the #1 disease factor of the 21st century?



What is the definition of aging ?

can be defined as a progressive, generalized impairment of function resulting in a loss of adaptative response to a stress and in a growing risk of age-associated disease


By 2050, what will be the situation of the global population ?

The population of older people will exceed that of children


What is the historical precedent of the phenomenon of aging population

There is no historical precedent


What explains more of the increase in deaths due to cancer and heart disease ?

People weren't affected by them because they didn't live long enough to get them


What is the exponential increase of life expectancy due to ? (2 main factors)

modern medicine, more precisely penicillin
general societal hygiene


What is the percent decline in physical strength and senses every year ?



What is the percentage of people over 65 that are obese ?



What are the 3 major causes of death in old age ?

Heart disease, cancer, stroke


What is fluid intelligence ? how does it change in old age ?

fluid intelligence is the ability to solve abstract relational problems, ability to solve new problems, use logic in new situations, and identify patterns
it decreases with age


What is crystallized intelligence ? how does it change in old age ?

ability to use learned knowledge and experience, retrieving information from memory

decreases with age


What is senile dementia characterized by ?

altered personality
difficulty in relation to others
memory loss


When do adults stop growing new brain cells ?

Never. Recent research has shown that adults continue to grow them throughout their lives


How does higher education have an effect on later brain function ?

Adults with higher levels of education show significantly less atrophy of cerebral cortex


What types of memory decline in older adults ? What memory does not decline ?

Decline in episodic and working memory

Not so much in semantic memory (common knowledge)


What are the goals of successful aging when it comes to memory?

Not eliminating memory decline, but reducing it and adapting to it


What memory task are older people better at than younger adults ?

Prospective memory tasks, involves remembering to perform a planned action or intention at some future point in time


What is Hayflick's Cellular Clock Theory ?

That cells can divide a maximum of about 75-80 times
As we age, our cells become increasingly less capable of dividing.
Hayflick places upper limit of lifespan at about 120 years.


How is telomere research related to Cellular Clock Theory?

Telomeres are DNA sequences that cap chromosomes, and each time a cell divides, telomeres become shorter and shorter.
Age-related telomere erosion linked with impaired ability to recover from stress and an increased rate of cancer.


How is compassion related to telomeres and the cellular clock theory?

compassion increases telomerase, which fixes telomeres


How is the Cellular Clock Theory related to injury repair ?

Injuries heal less quickly in older people because the cells divide less quickly


What is the Hormonal Stress Theory?

Aging in the body's hormonal system may lower resilience to stress and increase likelihood of disease.
With age, hormones stimulated by stress that flow through HPA system remain elevated longer than when we were younger.
Prolonged, elevated levels of stress-related hormones associated with increased risks for many diseases including heart disease and cancer.


What is the Free-Radical Theory?

injury caused by free radicals initiates a self-perpetuating cycle in which oxidative damage impairs mitochondrial function, which results in the generation of even greater amounts of oxygen free radicals


What is the chain of events in Free Radical Theory?

Oxidative cell damage leads to mitochondrial damage, releasing free radicals

DNA damage, cross-linking proteins, mitochondria damage
Forming age pigments
Impaired function


Is the frailty of old age reversible ?



What are the three most common stresses for older people

- diseases
- loss of social status after retirement
- death of spouse/child/sibling


How much time does it take to accept loss and start normal interaction ?

1 year


What is the main abused substance in older adults ?



What is memory?

Storage, retention, recall of information including past experiences, knowledge, thoughts


How does functional capacity change with age? How does the right lifestyle influence this ?

It decreases, but won't change that much with the right lifestyle


What is the most important thing for successful aging ?

Physical activity


In the study that looks at cardio-respiratory fitness, risk factors, what is the group most at risk of dying ?

Low cardio-respiratory fitness, with 2-3 risk factors


In the study that looks at cardio-respiratory fitness, risk factors, how does exercise affect risk of death?

Even with 2-3 risk factors, exercise dramatically decreases risk of dying - the high cardiorespiratory fitness, 2-3 risk factor group has a low risk of dying


In the study that looks at cardio-respiratory fitness, risk factors, what were the risk factors considered ?

current smoking
SBP > 140 mmHg
Chol > or = 240 mg/dl