Actinobacillus Flashcards Preview

RUSVM Bacteriology Gram Negatives > Actinobacillus > Flashcards

Flashcards in Actinobacillus Deck (17):
1

Actinobacillus - General description

Member of Family Pasturellaceae - Gram negative coccobacillis - "Morse Code" appearance - facultative anaerobe - Oxidase positive - Most urease positive - CAMP positive with Staph aureus - Cannot live in environment, need carriers for transmission

2

Actinobacillus - Commensals

Upper respiratory & oral cavity - Opportunistic pathogens

3

Actinobacillus - target cells

Nasal cavity & tonsillar crypts (of carrier animals) ; Terminal bronchioles & alveoli (of pre-diseased animals) - Causes Lower Respiratory Tract diesease

4

Actinobacillus- Pathogenesis

Contamination--> Inflammatory response (LPS, Urease) --> Bacteria survives, colonize, replicates--> septicemia (capsule, OMP, RTX toxin) --> Full disease

5

Actinobacillus - Clinical signs

Suppurative lung lesions - Granuloma formation in ruminant tongue & lymph nodes (Wooden Tongue*****)

6

When I say Wooden Tongue, you say...

Actinobacillus! in ruminants (A. lignieresii)

7

A. ligniersii - in ruminants

Wooden/Timber tongue!!! - Normal flora of nasopharynx - Introduced by trauma (plant) - May interfere with food intake --> weight loss--> dehydration

8

Common confusion with A. ligniersii

Often confused with Lumpy Jaw (actinoMYCOSIS) - Actinomycosis in BONE / Actinobacillus in soft tissue

9

Actinobacillus in rams

A. seminis - Epididymitis in young rams - Purulent discharges

10

Actinobacillus in swine - causative species and disease patterns

A. pleuropneumoniae - A. suis - A. equuli - Pneumonia and septicemia of young pigs in cold months (crowding/poor ventilation)

11

Actinobacillus in swine - Acute presentation

High mortality - Septicemia- skin lesions as in swine erysipelas

12

Actinobacillus in horses

Pneumonia, mixed infections with Strept. equi - Septicemia - Sleepy Foal Disease - A. equuli, Navel Ill - good hygiene practices important

13

What causes Sleepy Foal disease in equines?

A. equuli

14

Wooden tongue pathology

A. ligniersii - Cell-mediated Hypersensitivity - ABs in colostrum for piglets & foals - Ab's against RTX - Vaccine protects against homologous serotypes only - Eliminate carrier sows

15

Actinobacillus Fastidious-ness

Growth on blood agar requires V factor (NAD-dependent****)

16

Actinobacillus on MacConkey agar

Most grow, A. pleuropneumoniae doesn't

17

Actinobacillus Tx -

Antimicrobials - Iodides orally or IV for wooden tongue