Name the species Flashcards Preview

RUSVM Bacteriology Gram Negatives > Name the species > Flashcards

Flashcards in Name the species Deck (33):
0

Polysaccharide capsule

S. Pneumoniae

1

M protein/ fimbriae

Group A Streptococci

2

Surface slime / biofilm

Pseudomonas aeruginosa

3

O polysaccharide

LPS of E. Coli

4

K antigen / Vi antigen

E. Coli and Salmonella typhi

5

Cell-bound or soluble Protein A

Staph. Aureus

6

Protein A mechanism

Attaches to Fc region of IgG, blocks cytophilic domain, can't bind cell, IgG no longer capable of opsonization

7

Part of cell wall released to inhibit cell fusion

Mycobacterium Tuberculosis

8

Phagolysosome formation inhibited in phagocyte

Chlamydiae - L. pneumophila - Salmonella typhimurium

9

Survival inside phagolysosome - Waxy, hydrophobic cell wall - MYCOLIC ACIDS

Mycobacteria

10

Survival inside phagolysosome - LPS of cell wall

B. abortus

11

Survival inside phagolysosome - catalase & superoxide dismutase

B. Abortus, S. Aureus

12

Survival inside phagolysosome - poly-D-glutamate capsule

Bacillus anthracis

13

Escape phagolysosome - phospholipase A degradation of membrane

Rickettsiae

14

Survival inside phagolysosome - Listeriolysin O (pore-forming) & two phospholipase C types, polymerization of actin cytoskeleton for movement through cell

Listeria monocytogenes

15

Survival inside phagolysosome - lyse phagosomal vacuole, induce actin cytoskeleton polymerization for movement & spread

Shigella

16

Killing phagocyte before ingestion - secrete pore formers (hemolysis/ leukocydins)

Gram positive pathogens

17

Killing phagocyte before ingestion - produce streptolysin --> lysosomes explode into cell cytoplasm

Streptococci

18

Killing phagocyte before ingestion - produces leukocidins --> discharge of lysosomal granules

Staphylococci

19

Killing phagocyte before ingestion - exotoxin A. (Who secretes it? What does it do?)

Pseudomonas aeruginosa - disrupts cell equilibrium and consumes ATP reserves needed for engulfment if things

20

How does Neisseria gonorrhoeae maintain antigenic diversity

Change fimbriae antigen confirmation during infection. "Pili switching" (phase variation) rapid turning on/off genes controlling pili

21

How does Borrelia recurrentis maintain antigenic variation?

Relapsing fever by multiplying bacteria in tissues, bacteria then "disappear" (hide), fever falls until mutant arises again

22

Factor H binding proteins - complement evasion (how? Which species use this?)

Bind Factor H so it can't bind C3b so no complement.
- B. Burgdorferi (Erp proteins) and Leptospira interrogans (LfhA)

23

Ringworm

Dermatophytes! Microsporum, Trichosporum spp.

24

Feline ringworm

Microsporum Canis. (Yes, canis! And they are the main reservoir)

25

Favus or White Comb

Avian ringworm: Microsporum Gallinae

26

Red growth in dermatophyte test medium (DTM)

Indicates growth of dermatophyte

27

Ringworm in cow

T. Verrucosum

28

Ringworm in pigs

T. Nanum

29

Dermatomycoses

Malassezia spp., (pachydermatis & nana) , Trichosporon (not trichophyton the dermatoPHYTE). Geotrichum candidum.

30

Subcutaneous mycoses

Sporotrichosis (sporothrix schenkii) - Pythiosis - chromoblastomyxisis & Phaeohyphomycosis - mycetomas

31

African Horse Farcy

Histoplasma capsulatum var farciminosum. Granulomatous skin lesions

32

Pythiosis

Oomycoses - stramenophiles (not fungi!). - EDx: Pythium insidiosum