Adenosine Flashcards
1
Q
adenosine target
A
G-protein coupled receptors on neurons
2
Q
1st activity
A
activates A1 receptors (found on neurons and keep brain awake)
neurons become less active
3
Q
2nd activity
A
activates A2A receptor
found on neurons that initiate sleep
neurons become more active
4
Q
physiology
A
combination of the activation of the 2 receptors means weaker wake signal and stronger sleep signal
feel more refreshed when you wake up, due to the fact you have less adenosine when you wake
5
Q
clinical
A
used to bring heart rate back to normal rhythm
decreases heart rate
delay action potential in the SAN
6
Q
administration
A
IV
7
Q
side effects
A
diarrhoea
warm feeling
nausea
passing of gas
8
Q
used in treatment for
A
scintigraphy
supra ventricular tachycardia
