Picolax Flashcards
1
Q
drug classification
A
stimulant laxative
sodium picosulfate
2
Q
target
A
colonic mucosa after being metabolised by sulfatase 2
3
Q
mechanism of action
A
hydrolysed by colonic bacterial enzyme sulfatase 2 to form active metabolite BHPM
acts directly on the colonic mucosa to stimulate colonic peristalsis
inhibits absorption of water and electrolytes and increases their secretion into the intestinal lumen
4
Q
used in
A
cleaning the colon as preparation for colonoscopy in adults
5
Q
side effects
A
gastrointestinal discomfort
headache
nausea
