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Medicine: Drugs > Diclofenac > Flashcards

Diclofenac Flashcards

1
Q

classification

A

NSAID

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2
Q

used to treat

A

OA and RA

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3
Q

mechanism of action

A

inhibits COX 1 and 2 pathways
reduces prostaglandin G2 production
modulates nociception
activates G protein coupled EP1 receptor leading to increased activity of phospholipase C pathway
releasing intracellular Ca2+ which causes action potential and activates pKa

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Medicine: Drugs (38 decks)

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