Flashcards in Analgesia Deck (21):
Lidocaine- receptors and use?
Large animal local and systemic anesthetic used to control ventricular arrhythmias, adjunctive analgesia, GI prokinetic, and anti inflammatory
Bupivacaine - use and cautions?
Large animal local anesthetic - MOST CARDIOTOXIC
Diagnostic nerve block in horses
Procaine - cautions
Toxic- can cause CNS stimulation - DONT GIVE IV!!
Topical ophthalmic that allows for corneal and conjunctival manipulation
NSAIDs - receptors and use?
Inhibit cyclooxygenase enzymes for anti inflammatory, analgesic, antipyretic effects, anti thrombotic effects, and anti neoplastic effects
Production of prostaglandins that play an important role in normal homeostasis
Inducible prostaglandins produced during inflammation
COX-1 selective inhibitors
non specific COX inhibitors
COX-2 preferential inhibitors
COX-2 selective inhibitors
Flunixin Meglumine "Banamine" - use?
Soft tissue disease in horses and CATTLE
ONLY NSAID labeled in cattle
DO NOT use in small animal
Phenylbutazone "Bute" - use?
Used for musculoskeletal pain in horses
NOT LABELED IN CATTLE!
Carprofen, Meloxicam, Deracoxib - receptors and use?
COX-2 preferential for use in small animals as analgesic and anti inflammatory
Firocoxib and Robenacoxib - use?
Firocoxib- paste in horses and chewable in dogs
Robenacoxib - ONLY product labeled for multiple IV doses in cats
Tramadol - receptors and use?
Weak mu agonist and serotonin and norepinephrine reuptake inhibitor, M1 antagonist - used an an oral analgesia
AVOID IN EPILEPTIC PATIENTS!!
Gabapentin- receptors and use?
Alters the calcium influx in neuronal cells - used for the control of neuropathic pain
Amantadine - receptors and use?
NMDA antagonist - used as a adjunctive analgesic in small animals
Other anti inflammatory & chondroprotective drugs:
Omega 3 fatty acids