Flashcards in Ophthalmic Deck (25):
Constrict the pupil - contraction of the iris sphincter muscle and ciliary body for lens accommodation for near vision - lifts the iris away from the trabecular meshwork and increases uveoscleral aqueous outflow
Cause pupil constriction which opens the drainage angle
Pilocarpine- receptors and use?
Direct acting parasympathomimetic that causes miosis - used in the treatment of glaucoma and keratoconjunctivitis sicca and the diagnosis of parasympathomimetic lesions
Physostigmine and Demecarium - receptors and use?
Indirect acting parasympathomimetics that increase uveascaleral drainage
Echothiopate- receptors and use?
Indirect acting parasympathomimetic- causes a very long duration of miosis
Mydriatics - parasympatholytics
Atropine - receptors and use?
Direct acting parasympatholytic causes mydriasis and Cycloplegia- used in the reduction of pain associated with corneal or iris disease - can break up synechiae in uveitis
DO NOT use in glaucoma!!
Tropicamide- receptors and use?
Direct acting parasympatholytic causes mydriasis and Cycloplegia - used to dilate the pupil for ophthalmic exam and prevent adhesions after cataract surgery
Phenylephrine - receptors and use?
Alpha-1 agonist causes mydriasis through contraction of the iris muscle - used in perioperative cataract surgery and diagnosis and treatment of Horner syndrome
Lacromimetic agents - use?
Provide lubrication but do not perfectly replicate natural tears
Cyclosporine - use?
Treatment of canine Keratoconjunctivitis sicca
Tacrolimus- receptors and use?
Decreases T cell activation and works on patients that are not responsive to cyclosporine
Brimonidine - receptors and use?
Ophthalmic alpha agonist used in the treatment of glaucoma
Timolol- receptors and use?
Ophthalmic non selective beta antagonist used in glaucoma management
Dorzolamide - receptors and use?
Reversible inhibition of carbonic anhydrase to decrease aqueous humor production
Sulfonamide derivatives- cautions?
Hypersensitivity to sulfa
Latanoprost - receptors and use?
Topical prostaglandin agonist increases uveoscleral outflow by simulating prostaglandin receptors - used to topically treat glaucoma and reduce intraocular pressure
Glucocorticoids - dexamethasone and prednisone- use in the eye?
Manage inflammatory and immune mediated conditions noninfectious keratitis and uveitis
Topical NSAIDs: Flurbiprofen and Diclofenac - use?
Management of uveitis, keratitis, and inflammation associated with cataracts
Gancyclovir - use?
Antiviral used to manage feline viral infection and reserved for more severe cases
Treatment of fungal keratitis and conjunctivitis
Proparacaine- receptors and use?
Topical anesthetic that blocks sodium channels to prevent axonal depolarization used to decrease corneal sensation to allow for diagnostic evaluation