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Flashcards in Anemia treatment\ Deck (18):
1

hemolytic anemia treatment

transfusions
EPO

2

iron deficiency anemia treatment

ferrous sulfate
ferro-folgamma

3

hepcidin

acute phase reactant stimulated by IL6 and TNFalpha
down regulates ferroportin leading to iron sequestration in splenic macrophages

4

siltuximab

monoclonal IL6 antibody that decreases hepcidin expression

5

tocilzumab

IL6 receptor antagoinst

6

treatment of anemia of chronic disease

siltuximab
tocilzumab
steroids

7

drugs causing megaloblastic anemia

oral contraceptives
anticonvulsants

8

treatment of sideroblastic anemia

B6

9

sickle cell treatment

hydroxyurea
gene insertions
L-arginine + L-n-acetyl cystein

10

hydroxyurea

induces HbF production

11

L-arginine + L-n-acetyl cysteine

generates NO which increases oxygenation

12

drugs that cause anemia

chemo drugs
AZT
amphotericin B
ethanol
nitrofurantoin

13

ferocon

iron, vitamin C, vitamin B12, folic acid, intrinsic factor

14

erythropoietin

stimulates RBC production, from kidneys

15

types of erythropoietin

epoetin alpha, beta, omega
darbepoetin-alpha 9

16

darbopoetin-alpha 9

longer half life
higher potency

17

indications for EPO

chronic renal failure
anemia in cancer patients
surgery patients
AIDS patients on AZT

18

EPO cautions

heart disease
HTN
CHF
kidney disease/dialysis
history of stroke, heart attack, blood clots
blood cell/clotting disorder
cancer
epilepsy