Heme Lab Testing Flashcards Preview

Block 6 > Heme Lab Testing > Flashcards

Flashcards in Heme Lab Testing Deck (60):
1

EDTA and citrate

anticoagulants in sample tubes

2

MCV

mean cell volume
average RBC volume

3

RBC

red blood cell count

4

Hb

converts Hb to hemoglobin cyanide and measures the abosrption

5

Hct

hematocrit
MCV x RBC

6

MCHC

mean cell hemoglobin concentration
average mass of Hb per cell
Hb/RBC

7

spurious thrombocytopenia

platelets stick to white cells which appears as a reduction in platelet count

8

MPV

mean platelet volume

9

CBC with differential

complete blood count including #/% of
lymphocytes
monocytes
neutrophils
eosinophils
basophils

10

appearance of normal red cells

pink rim that is 2/3 the diameter
diameter 7-8 um

11

neutrophil

large
filled with fine granules
5 nuclear lobes

12

band cell

immature neutrophil
horseshoe nucleus
more granulation

13

left shift

more bands
indicates infection

14

RDW

red cell distribution width
range of RBC sizes

15

RDW is increased in

most anemias

16

neutrophil count is increased in

acute bacterial infections

17

lymphocyte

same size as RBC
nucleus takes up most of cell

18

lymphocyte elevation in

chronic infection
acute viral disease
some lymphomas

19

atypical lymphocytes

look similar to monocytes
BUT nucleus is indented and the cell forms around RBC

20

atypical lymphocytes are elevated in

mononucleuosis

21

monocyte

very large
blue
cytoplasm has vacuoles
nuclear cleft

22

monocytes elevated in

chronic infections
collagen vascular disease
some lymphomas

23

eosinophil

bright red granules
bilobed nucleus

24

eosinophils elevated in

atopic reactions
parasite infections
hodgkin lymphoma

25

basophil

smaller than neutrophil
basophilic (blue) granules block nucleus
rare

26

basophils elevated in

CML

27

band count vs absolute neutrophil count

band count- hard to get
ANC- total white count * neutrophils- better for monitoring infection

28

low ANC

low absolute neutrophil count
risk for infection

29

reticulocyte

immature RBC, larger
non nucleated
RNA fragments seen with special stain

30

reticulocyte count used for

assessing bone marrow function

31

reticulocyte count corrected for anemia

% reticulocytes x patient Hct/normal Hct

32

what is elevated if reticulocyte count is elevated

MCV

33

macrocytes

large RBC

34

microcytes

small RBC

35

spherocytes

round RBC
loss of central area of pallor

36

shistocytes

helmet looking- semicircle with pointy ends

37

shistocyte presence indicates

microangiopathic hemolytic anemia

38

ovalocytes

oval RBC

39

ovalocyte presence indicates

hereditary ovalocytosis
iron deficiency
thalassemia

40

drepanocytes

sickle cells

41

ancanthrocyte

spur cell
irregular thorn-like projections
no area of central pallor

42

ancanthrocyte presence indicates

advanced liver disease
malnutrition

43

echinocyte

burr cell
regular thorny projections

44

condocyte

target cell
leptocyte
excess membrane that folds on itself and Hg gets pushed to center

45

condocyte presence caused by either

reduced Hb content
increased RBC membrane

46

causes of reduce Hb content

thalassemia
hemoglobinopathy
iron deficiency anemia

47

causes of increased RBC membrane

post splectomy
liver disease

48

rouleaux

chain of RBC

49

cause of rouleaux

monoglobinopathy

50

Dohle body

ER bounced at cell periphery
reactive- in infections

51

Pelter-Huet cells

bilobed neutrophil nucleus
myelodysplastic syndromes

52

Howell Jolly body

RBC with DNA in int

53

cause of Howell Jolly body

post splectomy
megaloblastic anemia
hemolytic anemia

54

Howell Jolly body presence = risk of

encapsulated bacterial infections

55

hyperhsegmented neutrophil

6+ lobed nucleus

56

hyperhsegmented neutrophil association

megaloblastic anemia

57

cause of basophilic stippling

thalassemia
lead poisoning
5' pyridine nucleotides deficiency
liver disease
megaloblastic anemia

58

anisocytosis

RBC size variation

59

poikilocytosis

shape variation

60

hypochromic

low Hb