RBC Disorder Matching Flashcards Preview

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Flashcards in RBC Disorder Matching Deck (32):
1

shistocyte

microahgioathic hemolytic anemia

2

polychromasia

reticulocytosis

3

band neutrophil

infection

4

basophilic stippling

lead poisoning

5

acanthocyes

liver disease

6

dole bodies

infection

7

Howell Jolly body

splenectomy

8

Pelter-Huet cell

myelodysplastic synddromes

9

rouleau

plasma cell myeloma

10

red cell agglutinates

cold agglutinin disease

11

spherocytes

autoimmune hemolytic anemia

12

hypochromia

iron deficiency anemia

13

macrocytosis

B12 deficiency

14

neutrophil hyperlobation

B12 deficiency

15

paroxysmal nocturnal hemoglobinuria

clonal disorder of PIG-A gene making RBCs sensitive to complement mediated lysis

16

sickle cell disease

point mutation resulting in abnormal hemoglobin and reduced RBC survivial

17

thalassemia major

genetic disorder causing reduced synthesis of global chains

18

warm autoimmune hemolytic anemia

production of RBC autoantibody causing extravascular hemolysis at body temperature

19

cold agglutinin syndrome

production of RBC autoantibody on exposure to mycoplasma pneumoniae or EBV

20

paroxysmal cold hemoglobinuria

autoimmune hemolytic disorder associated with IgG biphasic hemolysin

21

hereditary spherocytosis

autosomal dominant genetic defect in ankyrin causing RBC membrane fragility

22

aplastic crisis

red cell aplasia induced by parvovirus B19 infection

23

G6PD deficiency

X linked enzyme deficiency resulting in acute hemolysis on exposure to oxidative compounds

24

immune thrombocytopenia purpura

autoantibody coats patient's platelets causing removal from circulation

25

neonatal alloimmune thrombocytopenia

alloantibody coats patient's platelets causing destruction

26

heparin induced thrombocytopenia

antibody against heparin-PF4 complex leading to thrombocytopenia and thrombosis

27

thrombotic thrombocytopenia purpura

autoantibody against ADAMTS13 leading to thrombocytopenia and MAHA

28

Glanzmann thrombobasthenia

Genetic lack of GP2b3a platelet receptor for vWF

29

bernard Soulier syndrome

genetic lack of GP1b platelet receptor for fibrinogen

30

von Willebrand disease

platelet function defect where platelets do not normally bind to injured endothelium through the GP1b receptor

31

Hemophilia B

genetic deficiency of factor 9 production

32

disseminated intravascular coagulation

coagulopathy associated with abnormal bleeding and clotting