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FarmaaaA > Antiretrovirales > Flashcards

Antiretrovirales Flashcards

1
Q

Esquema TARA

A

Incluye 3 o mas meds de dos clases distintas
1er linea: 2 NITI + 1 INNTI
(P.e. Emtricitabina + tenofovir + efavirenz)
Alternativo: 2 INNTI + 1 Inhib. de proteasa

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2
Q

Zi Dice, Estoy Zal, La Abrazo, Te Extrañe

A

Nucleótidos inhibid. de transcriptasa inversa
Zidovudina
Didanosina
Estavudina
Zalcitabina
Lamivudina
Abacavir
Tenofovir
Emtricitabina

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3
Q

Convierten ARN viral en ADN proviral, previenen infecciones pero no erradican

A

NITI

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4
Q

Se utiliza como prevención de transmisión de VIH de madre al feto, y en trabajadores sanitarios

A

Zidovudina

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5
Q

EA
Zidovudina

A

Mielosupresión
Acidosis lactica

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6
Q

Analogo nucleosido de purina para VIH

A

Didanosina

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7
Q

EA
Didanosina

A

Pancreatitis, neuropatía, ginecomastia

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8
Q

Analogo nucleosido de citidina, para VIH, VHB, y VPH

A

Lamivudina

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9
Q

EA
Lamivudina

A

Pancreatitis en bbs

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10
Q

Analógo sintetico de guanosina para VIH, afectado por el etanol

A

Abacavir

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11
Q

EA
Tenofovir

A

Flatulencia, IR, sd. Fanconi

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12
Q

Analogo de citidina para VIH

A

Emtricitabina

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13
Q

EA
Emtricitabina

A

Acumulación de ácido láctico, hiperpigmentación de la piel.

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14
Q

Se unen a la subunidad p66 de la transcriptasa inversa

A

INNTI

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15
Q

EA
INNTI

A

Exantemas

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16
Q

N-EFasto y DELAV Entrar en abRIL

A

INNTI
Nevirapina
Efavirenz
Delavirdina
Etravirina
Rilpivirina

17
Q

Tx de VIH 1 en niños y profilaxis en embarazadas

A

Nevirapina

18
Q

EA
Efavirenz

A

Sueños vividos, teratogeno

19
Q

Inhiben competitivamente la aspartil proteasa viral, INDUCEN CYP3A4 (excepto uno)

A

Inhibidores de la proteasa

20
Q

Inhibidor de la proteasa, REFORZADOR, q INHIBE CYP3A4

A

Ritonavir

21
Q

Inhibidores de la proteasa

A

TERMINAN EN -NAVIR

22
Q

EA
Inhibidores de la proteasa

A

Hipertrigliceridemia, hipercolesterolemia, especto cushingnoide, ginecomastia

23
Q

EA
Indinavir

A

Nefrolitiasis y hepatotoxicidad

24
Q

No se combina con Ritonavir

A

Nelfinavir

25
Q

EA
Tipranavir

A

Hemorragia Intracraneal

26
Q

MAR de ENFermos

A

Inhibidores de entrada
Maraviroc
Enfuvirtida

27
Q

Tx con evidencia de virus con tropismo de CCR5

A

Maraviroc

28
Q

ÚNICO PARENTERAL ANTIRETROVIRAL

A

Enfuvirtida

29
Q

Conserva actividad contra virus resistentes a diferenicia de antiretrovirales

A

Raltegravir

FarmaaaA (57 decks)

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