Opioides Flashcards

1
Q

Metabolito de la morfina detectado en ADP

A

m6g

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2
Q

UT Morfina

A

Libera histamina, antitusigeno, espasmo de visceras huecas, anestesia raquidea
AGONISTA MOR Y KOR morkina

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3
Q

EA
Morfina

A

Estreñimiento

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4
Q

UT
Metadona

A

Dolor cronico, dolor neuropatico, dependencia de heroina
AGONISTA MOR

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5
Q

Tratamiento de abstinencia por opioides

A

Metadona + naloxona

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6
Q

UT
Fentanilo

A

AGONISTA MOR
Acción rapida, anestesico de tiempo corto

ESTA EN PARCHES Y ES 100 VECES MAS POTENTE Q MORFINA

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7
Q

Principal agonista opioide que actua en receptores MOR, KOR y DOR

A

Levorfanol, y dextrorfano

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8
Q

UT Levorfanol y dextrofano

A

Antitusigeno
Puede inhibir NMDA y recaptura de 5HT/NE

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9
Q

UT Loperamida

A

Diarrea aguda y cronica

NO CRUZA BHE, glucoproteina P lo regresa

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10
Q

Contraindicación
intrarraquideo con glicina

A

Sufentanilo y remifentanilo

son ULTRARRAPIDOOO

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11
Q

Opioide metabolizado por esterasas plasmaticas

A

Remifentanilo

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12
Q

Opioide que se retiro xq es cardiotoxico

A

Propoxifeno

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13
Q

UT
Hidrocodona

A

Px con pobre funcion renal, antitusivo

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14
Q

UT
Meperidina

A

Escalofrios postanestesicos, cruza placenta

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15
Q

Inhibe recaptura de NE y 5HT, metabolismo por CYP2D6 y CYP3A4

A

Tramadol

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16
Q

Metabolismo Buprenorfina

A

Agonista MOR y antagonista KOR y DOR

MOR - KOR + DOR +

17
Q

UT Buprenorfina

A

Quemados y debridaciones

18
Q

EA Buprenorfina

A

Depresión respiratoria y sd. de abstinencia

19
Q

UT Butorfenol

A

Dolor agudo postquirurgico, migraña

20
Q

VA Butorfenol

A

IV o IM, Nasal, tarda menos de 10 minutos

21
Q

Analgesia a nivel de receptores de medula

A

Pentazocina

22
Q

Triada intoxicación por opioides

A

Depresión respiratoria, pupilas puntiformes, coma

23
Q

UT Naloxona

A

Sobredosis de opiaceos potentes aguda

24
Q

EA Naloxona

A

Aumento de LH, FSH, ACTH, PRL y baja el apetito, estreñimiento

25
Q

UT Naltrexona

A

Tx en dependencia por alcohol

26
Q

UT Alvimopan

A

Estreñimiento por opioides

27
Q

UT Dextrometorfano

A

Antitusigeno, antagonista NMDA

28
Q

Agonistas MOR

A

Todos excepto ag/ant y ant puros

29
Q

Agonistas/antagonistas

A

Buprenorfina M+ K y D -
Nalbufina, butorfanol y pentazocina M - K +

30
Q

Antagonistas puros

A

Naloxona
Naltreoxona