Quinolonas Flashcards

1
Q

MA
Quinolonas

A

Inhiben síntesis de ADN
Topoisomerasa IV → (+)
ADN girasa → (-)

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2
Q

EA
Quinolonas

A

Inhiben metabolismo de teofilina
Artralgias
Rotura del tendón de Aquiles

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3
Q

1er gen
Quinolonas

A

Ac. nalidixico

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4
Q

2da gen
Quinolonas

A

CLON
Ciprofloxacino
Lomefloxacino
Ofloxacino
Norfloxacino

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5
Q

3er gen
Quinolonas

A

Levofloxacino
Tosufloxacino

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6
Q

4ta gen
Quinolonas

A

Moxifloxacino
Gatifloxacino
Gemifloxacino
Balofloxacino

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7
Q

Se utiliza con fenazopiridina para IVUS no complicadas

A

Acido nalidixico

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8
Q

Inhibe solo a ADNgirasa no fluorada

A

Acido nalidixico

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9
Q

Inhiben solo topoisomerasa IV

A

Ciprofloxacino y norfloxacino

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10
Q

no. 1 Prevención/tx de CARBUNCO/antrax/bacillus antracis

A

Ciprofloxacino

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11
Q

CI
Ciprofloxacino

A

Tizanidina

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12
Q

Quinolonas
Se utilizan en el tratamiento de IVUS

A

Acido nalidixico + fenazopiridina
Lomefloxacino
Norfloxacino

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13
Q

UT
Norfloxacino

A

IVUs
DIARREA DEL VIAJERO
#2 cólera

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14
Q

Quinolona
no. 1 NEUMONIA INTRA/EXTRA hospitalaria

A

Levofloxacino
IN + ceftria y claritro
EX + amoxi y clavu

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15
Q

Especto de quinolonas de 4ta gen

A

Gram + (s. pneumoniae) y buena actividad pero no tan efectivo con anaerobios (p. aeruginosa)

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16
Q

Quinolona
Útil para infecciones intraabdominales complicadas (b. fragillis)

A

Moxifloxacino

17
Q

Quinolona
Útil para TB resistente

A

Moxifloxacino

18
Q

Quinolona
NO aprobada para IVUS

A

Moxifloxacino

19
Q

EA
Moxifloxacino

A

Prolongan QT
TQ M

20
Q

Quinolona
Preparación oftalmica para conjuntivitis bacteriana

A

Gatifloxacino

21
Q

EA
Gatifloxacino

A

Toxicidad en uso sistémico
Hipo/hiperglucemia