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FarmaaaA > Hipolipemiantes > Flashcards

Hipolipemiantes Flashcards

1
Q

Mecanismo de acción
Estatinas

A

Inhiben HMG-CoA reductasas

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2
Q

EA Estatinas

A

Rabdomiolisis al combinar con fibratos

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3
Q

Estatina profarmaco de la lovastatina

A

Lovastatina→Lactona

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4
Q

Estatina con SV larga

A

Atorvastatina

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5
Q

Tx de hipercolestorelemia con IR

A

Atorvastatina

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6
Q

Tx indicado en mayores de 8 años, hipercolestoremia

A

Pravastatina

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7
Q

Disminuye su eliminacion con gemfibrozilo

A

Pitavastatina

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8
Q

Activadores del proliferador peroxisomico PPAR Alfa

A

Derivados del acido fibrico/Fibratos

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9
Q

Tx de hipertrigliciridemia + riesgo de pancreatitis

A

Fibratos

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10
Q

EA Fibratos

A

Riesgo de litos y rabdomiolisis

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11
Q

Fibrato más litogenico

A

Clofibrato

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12
Q

Medicamentos
Fibratos

A

Clofribato
Gemfribrozilo
Fenofibrato

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13
Q

Mecanismo de acción Resinas

A

Secuestran acidos biliares

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14
Q

Se utilizan en niños por que aumentan los trigliceridos

A

Resinas

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15
Q

Medicamentos
Resinas

A

Las colas
Colesevelam
Colestiramina
Colestipol

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16
Q

Como se administran las resinas

A

en polvito

17
Q

Medicamentos
Antagonistas del colesterol

A

Orlistat
Ezetimibe

18
Q

EA Antagonistas del colesterol

A

Esteatorrea

19
Q

Inhibe a la proteina similar a Niemann Pick 1 (NPC1L1)

A

Ezetimibe

20
Q

Inhibe la lipasa pancreatica y disminuye TAG

A

Orlistat

21
Q

Inhibe lipolisis por la lipasa sensible a hormonas, incrementa HDL

A

Niacina B3

22
Q

EA Niacina

A

Acantosis nigricans Y T pone rojito

23
Q

Inhiben la convertasa de propoteina subtilisna/kexina tipo 9 (Anti PSCK9)

A

Evolocumab
Alirocumab

FarmaaaA (57 decks)

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