Autonomic Drugs Flashcards
(114 cards)
1
Q
Bethanechol: receptor
A
Muscarinic agonist
2
Q
Bethanechol: 2 uses
A
Post-operative ileus
Urinary retention
3
Q
Carbachol: receptor
A
Muscarinic agonist
4
Q
Carbachol: 2 uses
A
glaucoma
pupillary contraction
5
Q
Pilocarpine: receptor
A
Muscarinic agonist
6
Q
Pilocarpine: 2 uses
A
glaucoma, pupillary contraction
7
Q
Methacholine: receptor
A
muscarinic agonist
8
Q
Methacholine: use
A
asthma challenge test
9
Q
Neostigmine: receptor
A
anticholinesterase
10
Q
Neostigmine: 4 uses
A
post-operative/neurological ileus
urinary retention
Myasthenia Gravis
reversal of NMJ blockade
11
Q
Pyridostigmine: receptor
A
anticholinesterase
12
Q
Pyridostigmine: use
A
Myasthenia Gravis
13
Q
Edrophonium: receptor
A
anticholinesterase
14
Q
Edrophonium: use
A
diagnosis of myasthenia gravis
15
Q
Physostigmine: receptor
A
anticholinesterase
16
Q
Physostigmine: 2 uses
A
glaucoma
atropine overdose
17
Q
Echothiophate: receptor
A
anticholinesterase
18
Q
Echothiophate: use
A
glaucoma
19
Q
Donepezil: receptor
A
anticholinesterase
20
Q
Donepezil: use
A
Alzheimer’s disease
21
Q
Galantamine: receptor
A
anticholinesterase
22
Q
Galantamine: use
A
Alzheimer’s disease
23
Q
Rivastigmine: receptor
A
anticholinesterase
24
Q
Rivastigmine: use
A
Alzheimer’s disease
25
Atropine: receptor
muscarinic antagonist
26
Atropine: 3 uses
Insecticide toxicity
dilation of eyes, cycloplegia
decreases secretions during sedation
27
Homotropine: receptor
muscarinic antagonist
28
Homotropine: use
mydriasis
29
Tropicamide: receptor
muscarinic antagonist
30
Tropicamide: use
mydriasis
31
Pralidoxine: receptor
chemical antagonist, regenerates cholinesterase
32
Pralidoxine: use
Insecticide toxicity (use with atropine)
33
Ipratroprium: receptor
muscarinic antagonist
34
Ipratroprium: use
asthma, COPD
35
Benztropine: receptor
muscarinic antagonist
36
Benztropine: use
Parkinson's
37
Scopolamine: receptor
muscarinic antagonist
38
Scopolamine: use
motion sickness
39
Oxybutynin: receptor
muscarinic antagonist
40
Oxybutynin: use
reduces urgency in mild cystitis, bladder spasms
41
Glycopyrrolate: receptor
muscarinic antagonist
42
Glycopyrrolate: use
decrease airway secretions in surgery
43
Methscopolamine: receptor
muscarinic antagonist
44
Methscopolamine: use
peptic ulcers
45
Propantheline: receptor
muscarinic antagonist
46
Propantheline: use
Peptic ulcers
47
Hexamethonium: receptor
Nicotinic receptor ganglionic blocker (para and symp blockade)
48
Hexamethonium: use
experimental, prevents vagal reflex to drugs
49
Epinephrine: receptors
alpha 1/2
| beta 1/2
50
Epinephrine: 4 uses
Anaphylactic shock
open angle glaucoma
asthma
hypotension
51
Norepinephrine: receptors
alpha 1/2 more than beta 1
52
Norepinephrine: use
Septic shock, decreases renal perfusion
53
Isoproterenol: receptors
beta 1/2
54
Isoproterenol: use
AV block (rarely used)
55
Dopamine: receptors
D1/2 more than beta more than alpha
56
Dopamine: 2 uses
heart failure, increases renal perfusion
57
Dobutamine: receptors
beta 1 more than beta 2
58
Dobutamine: 3 uses
cardiogenic shock
heart failure
stress testing
59
Phenylephrine: receptors
alpha 1 more than alpha 2
60
Phenylephrine: 3 uses
pupillary dilation
vasoconstriction, nasal decongestion
epistaxis
61
Metaproterenol: receptors
beta 2 more than beta 1
62
Metaproterenol: use
bronchodilation (asthma)
63
Albuterol: receptors
beta 2 more than beta 1
64
Albuterol: use
acute asthma
65
Levalbuterol: receptors
beta 2 more than beta 1
66
Levalbuterol: use
acute asthma
67
Salmeterol: receptors
beta 2 more than beta 1
68
Salmeterol: use
asthma long-term treatment
69
Terbutaline: receptors
beta 2 more than beta 1
70
Terbutaline: 2 uses
asthma
| reduction of premature uterine contractions
71
Ritodrine: receptor
beta 2
72
Ritodrine: use
reduction of premature uterine contractions
73
Amphetamine: mechanism
releases stored catecholamines (indirect sympathomimetic)
74
Amphetamine: 4 uses
narcolepsy
obesity
ADD
major depressive disorder
75
Ephedrine: mechanism
releases stored catecholamines
76
Ephedrine: 3 uses
Nasal decongestion
Urinary incontinence
Hypotension
77
Cocaine: mechanism
Reuptake inhibitor (NA, dopamine, serotonin)
78
Cocaine: 2 uses
Vasoconstriction in nose
| Local anesthesia
79
Clonidine: receptor
Alpha 2 agonist
80
Clonidine: use
renal disease (short acting)
81
Alpha-methyldopa:receptor
Alpha 2 agonist
82
Alpha-methyldopa: use
renal disease
| High BP in pregnancy
83
-olols and -alols: receptor
Beta blockers
84
-olols and -alols: 2 uses
High BP
| comorbidities for heart disease
85
Metroprolol: receptor
Beta blocker
86
Metroprolol: use
MI
87
Carbadolol: receptor
Beta blocker
88
Carbadolol: use
MI
89
Propranolol: receptor
Beta blocker (non-selective)
90
Propranolol: use
SVT
| thyroid storm
91
Esmolol: receptor
Beta blocker (beta 1)
92
Esmolol: use
SVT
93
Timolol: receptor
Beta blocker (non-selective)
94
Nadolol: receptor
Beta blocker (non-selective)
95
Pindolol: receptor
Beta blocker (non-selective)
96
Labetalol: receptor
Beta blocker (non-selective), alpha blocker
97
Acebutolol: receptor
Beta 1 selective blocker
98
Betaxolol: receptor
Beta 1 selective blocker
99
Esmolol: receptor
Beta 1 selective blocker
100
Atenolol: receptor
Beta 1 selective blocker
101
Metrprolol: receptor
Beta 1 selective blocker
102
Benefit of Beta 1 selective drugs
Less asthma exacerbation
103
Alpha 1 receptor action
vasoconstriction (block to dilate)
104
Alpha 2 receptor action
vasodilation (block to constrict)
105
Phenoxybenzanine: receptor
Non selective alpha blocker
106
Phenoxybenzanine: use
Pheochromocytoma (give before beta blocker)
107
Phentolamine: receptor
Alpha 1 blocker
108
Phentolamine: use
Pheochromocytoma (reversible)
109
-zosins: receptor
Alpha 1 blocker
110
-zosins: use
Hypertension
| Urinary retention in BPH
111
Tamisulisan: receptor
Alpha 1 blocker
112
Tamisulisan: use
Urinary retention in BPH
113
Mirtazapine: receptor
Alpha 2 blocker
114
Mirtazapine: use
Depression
| Causes sedation and increased appetite
