Autonomic Drugs Flashcards Preview

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Flashcards in Autonomic Drugs Deck (114):
1

Bethanechol: receptor

Muscarinic agonist

2

Bethanechol: 2 uses

Post-operative ileus
Urinary retention

3

Carbachol: receptor

Muscarinic agonist

4

Carbachol: 2 uses

glaucoma
pupillary contraction

5

Pilocarpine: receptor

Muscarinic agonist

6

Pilocarpine: 2 uses

glaucoma, pupillary contraction

7

Methacholine: receptor

muscarinic agonist

8

Methacholine: use

asthma challenge test

9

Neostigmine: receptor

anticholinesterase

10

Neostigmine: 4 uses

post-operative/neurological ileus
urinary retention
Myasthenia Gravis
reversal of NMJ blockade

11

Pyridostigmine: receptor

anticholinesterase

12

Pyridostigmine: use

Myasthenia Gravis

13

Edrophonium: receptor

anticholinesterase

14

Edrophonium: use

diagnosis of myasthenia gravis

15

Physostigmine: receptor

anticholinesterase

16

Physostigmine: 2 uses

glaucoma
atropine overdose

17

Echothiophate: receptor

anticholinesterase

18

Echothiophate: use

glaucoma

19

Donepezil: receptor

anticholinesterase

20

Donepezil: use

Alzheimer's disease

21

Galantamine: receptor

anticholinesterase

22

Galantamine: use

Alzheimer's disease

23

Rivastigmine: receptor

anticholinesterase

24

Rivastigmine: use

Alzheimer's disease

25

Atropine: receptor

muscarinic antagonist

26

Atropine: 3 uses

Insecticide toxicity
dilation of eyes, cycloplegia
decreases secretions during sedation

27

Homotropine: receptor

muscarinic antagonist

28

Homotropine: use

mydriasis

29

Tropicamide: receptor

muscarinic antagonist

30

Tropicamide: use

mydriasis

31

Pralidoxine: receptor

chemical antagonist, regenerates cholinesterase

32

Pralidoxine: use

Insecticide toxicity (use with atropine)

33

Ipratroprium: receptor

muscarinic antagonist

34

Ipratroprium: use

asthma, COPD

35

Benztropine: receptor

muscarinic antagonist

36

Benztropine: use

Parkinson's

37

Scopolamine: receptor

muscarinic antagonist

38

Scopolamine: use

motion sickness

39

Oxybutynin: receptor

muscarinic antagonist

40

Oxybutynin: use

reduces urgency in mild cystitis, bladder spasms

41

Glycopyrrolate: receptor

muscarinic antagonist

42

Glycopyrrolate: use

decrease airway secretions in surgery

43

Methscopolamine: receptor

muscarinic antagonist

44

Methscopolamine: use

peptic ulcers

45

Propantheline: receptor

muscarinic antagonist

46

Propantheline: use

Peptic ulcers

47

Hexamethonium: receptor

Nicotinic receptor ganglionic blocker (para and symp blockade)

48

Hexamethonium: use

experimental, prevents vagal reflex to drugs

49

Epinephrine: receptors

alpha 1/2
beta 1/2

50

Epinephrine: 4 uses

Anaphylactic shock
open angle glaucoma
asthma
hypotension

51

Norepinephrine: receptors

alpha 1/2 more than beta 1

52

Norepinephrine: use

Septic shock, decreases renal perfusion

53

Isoproterenol: receptors

beta 1/2

54

Isoproterenol: use

AV block (rarely used)

55

Dopamine: receptors

D1/2 more than beta more than alpha

56

Dopamine: 2 uses

heart failure, increases renal perfusion

57

Dobutamine: receptors

beta 1 more than beta 2

58

Dobutamine: 3 uses

cardiogenic shock
heart failure
stress testing

59

Phenylephrine: receptors

alpha 1 more than alpha 2

60

Phenylephrine: 3 uses

pupillary dilation
vasoconstriction, nasal decongestion
epistaxis

61

Metaproterenol: receptors

beta 2 more than beta 1

62

Metaproterenol: use

bronchodilation (asthma)

63

Albuterol: receptors

beta 2 more than beta 1

64

Albuterol: use

acute asthma

65

Levalbuterol: receptors

beta 2 more than beta 1

66

Levalbuterol: use

acute asthma

67

Salmeterol: receptors

beta 2 more than beta 1

68

Salmeterol: use

asthma long-term treatment

69

Terbutaline: receptors

beta 2 more than beta 1

70

Terbutaline: 2 uses

asthma
reduction of premature uterine contractions

71

Ritodrine: receptor

beta 2

72

Ritodrine: use

reduction of premature uterine contractions

73

Amphetamine: mechanism

releases stored catecholamines (indirect sympathomimetic)

74

Amphetamine: 4 uses

narcolepsy
obesity
ADD
major depressive disorder

75

Ephedrine: mechanism

releases stored catecholamines

76

Ephedrine: 3 uses

Nasal decongestion
Urinary incontinence
Hypotension

77

Cocaine: mechanism

Reuptake inhibitor (NA, dopamine, serotonin)

78

Cocaine: 2 uses

Vasoconstriction in nose
Local anesthesia

79

Clonidine: receptor

Alpha 2 agonist

80

Clonidine: use

renal disease (short acting)

81

Alpha-methyldopa:receptor

Alpha 2 agonist

82

Alpha-methyldopa: use

renal disease
High BP in pregnancy

83

-olols and -alols: receptor

Beta blockers

84

-olols and -alols: 2 uses

High BP
comorbidities for heart disease

85

Metroprolol: receptor

Beta blocker

86

Metroprolol: use

MI

87

Carbadolol: receptor

Beta blocker

88

Carbadolol: use

MI

89

Propranolol: receptor

Beta blocker (non-selective)

90

Propranolol: use

SVT
thyroid storm

91

Esmolol: receptor

Beta blocker (beta 1)

92

Esmolol: use

SVT

93

Timolol: receptor

Beta blocker (non-selective)

94

Nadolol: receptor

Beta blocker (non-selective)

95

Pindolol: receptor

Beta blocker (non-selective)

96

Labetalol: receptor

Beta blocker (non-selective), alpha blocker

97

Acebutolol: receptor

Beta 1 selective blocker

98

Betaxolol: receptor

Beta 1 selective blocker

99

Esmolol: receptor

Beta 1 selective blocker

100

Atenolol: receptor

Beta 1 selective blocker

101

Metrprolol: receptor

Beta 1 selective blocker

102

Benefit of Beta 1 selective drugs

Less asthma exacerbation

103

Alpha 1 receptor action

vasoconstriction (block to dilate)

104

Alpha 2 receptor action

vasodilation (block to constrict)

105

Phenoxybenzanine: receptor

Non selective alpha blocker

106

Phenoxybenzanine: use

Pheochromocytoma (give before beta blocker)

107

Phentolamine: receptor

Alpha 1 blocker

108

Phentolamine: use

Pheochromocytoma (reversible)

109

-zosins: receptor

Alpha 1 blocker

110

-zosins: use

Hypertension
Urinary retention in BPH

111

Tamisulisan: receptor

Alpha 1 blocker

112

Tamisulisan: use

Urinary retention in BPH

113

Mirtazapine: receptor

Alpha 2 blocker

114

Mirtazapine: use

Depression
Causes sedation and increased appetite