Flashcards in biochem 2 krebs cycle Deck (25)
What enzyme catalyses pyruvate to acetyl CoA?
what is the first subsrate in krebs cycle?
What is the first reaction of kreb's cycle?
condensation of Acetyl CoA by enzyme citrate synthase to create citrate by the addition of water and the byproduct CoASH
What is the second reaction of Kreb's cycle?
the movement of hydroxyl group on Carbon 2 of citrate to carbon 3 of Isocitrate catalyzed by aconitase
What is the third reaction of Kreb's cycle?
the oxidation and decarboxylation of isocitrate to give
1.NADH + (H+) & CO2
What is the catalyst of the third reaction?
What is the fourth reaction of Kreb's cycle?
The oxidation and decarboxylation of alpha-ketogluarate to produce
1. NADH + (H+) & CO2
with the addition of CoASH
What is the catalyst of the fourth reaction?
What forms at the ketone end of Succinyl CoA after the fourth reaction?
a high energy bond
What is the fifth reaction of Kreb's cycle?
substrate level phosphorylation of Succinyl CoA (no O2 needed) to produce
with the addition of GDP + P
What is the catalyst used for the fifth reaction?
What is the sixth reaction of Kreb's cycle?
oxidation of Succinate to produce (after the addition of FAD
1. FADH (2H)
What is the sixth reaction's catalyst?
What is the seventh reaction of Kreb's cycle?
hydration of fumarate to produce (after the addition of H2O) hydration duh!
1. Malate by the calalyst fumarase
What is the eighth and final reaction of Kreb's cycle?
oxidation of Malate to produce (after the addition of NAD+
1. NADH + (H+)
What is the catalyst of the eighth reaction?
What are the reaction steps that produce NADH + H+ or FADH (2H)
3. NADH + (H+)
4. NADH +(H+)
6. FADH (2H)
8. NADH +(H+)
What reaction (s) produce GTP?
What reactions produce CO2?
reaction 3 & 4
increased lactate produces _____
Where is the 3 NADH and 1 FADH being sent?
ETC electron transport chain for oxidative phosphorylation
What are the first 4 substates used in Kreb's cycle?
What are the first four catalysts used in Kreb's cycle?
1. citrate synthase
What are the last 5 substrates used in Kreb's cycle?
5. Succinyl CoA