Tumors Flashcards

1
Q

anaplasia

A

loss of cellular differentiation and function

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2
Q

atrophy

A

a wasting

decrease in size of an organ or tissue

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3
Q

benign

A

not recurrent or progressive

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4
Q

cachexia

A

a state of ill health

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5
Q

cancer

A

malignant neoplasm marked by uncontrolled growth and the spread by abnormal cells

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6
Q

cancer in epithleial cells

A

carcinomas

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7
Q

cancer in mesenchymal tissues

A

sarcomas

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8
Q

carcinoma in situ

A

a new growth or malignant tumor that occurs in epithelial tissue and do not extend beyond the basement membrane

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9
Q

carcinogen

A

any substance or agent that produces cancer or increases the risk of developing cancer

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10
Q

carcinogenises

A

the production or origin of cancer

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11
Q

co-carcinogen

A

a chemical or enviromental factor that enhances the action of a carcinogen

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12
Q

chemotherapy

A

the application of chemical reagents that have specific and toxic effect on a disease causing pathogen

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13
Q

contact inhibition

A

the natural process of arresting cell growth when two or more cells come into contact with each other

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14
Q

when does contact inhibition fail?

A

malignant neoplasia growth

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15
Q

embolus

A

clot that is moving in circulation

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16
Q

etiology

A

the study of the cause of disease

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17
Q

hemangioma

A

a benign tumor composed of newly formed blood vessels

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18
Q

hematoma

A

a swelling or mass of blood, usually clotted, confined to an organ

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19
Q

infiltration

A

the process of a substance passing into and being deposited within the substance of a cell

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20
Q

leukemia

A

a malignancy of the blood forming cells in the bone marrow

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21
Q

lymphadenopathy

A

disease of the lymph nodes

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22
Q

malaise

A

a generalized feeling of discomfort

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23
Q

malignant

A

growing worse, resisting treatment

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24
Q

metastasis

A

movement of cells from one part of the body to another

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25
neoplasm
a new formation of tissue
26
oncogenesis
tumor formation and development
27
oncogene
a potentially cancer inducing gene
28
prodromal
pertaining to the initial stage of a disease the interval b/w earliest symptoms and apperance of rash or fever
29
sarcoma
a cancer arising from connective (mesenchymal) tissue
30
sign
abnormally noted by an observer
31
stroma
the supporting tissue or matrix of and organ or tumor
32
symptom
abnormally noted by a patient
33
syndrome
a group of symptoms and signs of disordered function related to one another by means of some peculiarity
34
tumor
a swelling or enlargement, one of four classic signs of inflammation
35
tumor angiogenesis factor
a protein present in animal and human cancer tissue
36
tumor marker
a substance whose presence in blood serum serves as a biochemical indicator for the presence of a malignancy
37
benign tumor characteristics
1. grow by expansion
38
benign tumor characteristics
2. round, smooth, and regular to palpate
39
benign tumor characteristics
3. rarely cause severe problems
40
benign tumor characteristics
4. tend to grow slowly and not recur may cause pressure effects
41
benign tumor characteristics
5. histologically, benign tumors are well-differentiated, closely resembeling tissue of origin
42
Malignant tumor characteristics
1. grow by local invasion and infiltration with destruction of surrounding tissue
43
Malignant tumor characteristics
2. usually poorly circumscribed and unencapsulated
44
Malignant tumor characteristics
3. tumor often fixed to other surrounding tissues
45
Malignant tumor characteristics
4.rough and irregular to palpation, may cause ulceration
46
Malignant tumor characteristics
5. grow rapidly and difficult to remove surgically in their entirety
47
Malignant tumor characteristics
6. chief definitive feature of malignant tumors is their tendency to spread locally, and metastasis
48
Malignant tumor characteristics
7. histologically, malignancies are poorly differentiated aggressive tumors show frequent mitosis
49
what are intermediate tumors?
tumors that are between benign and malignant
50
examples of intermediate tumors
ganglioneuroblastoma | giant cell tumor
51
suffix meaning tumor
-oma
52
if naming a malignant tumor you must determine what?
the parent tissue
53
parent tissue = epithelial
carcinoma
54
parent tissue = connective tissue
sarcoma
55
suffix indicating a malignancy arising in embryoic tissue in precurser cells
-blastoma
56
T or F | lymphoma, leukemia, and myloma are all malignancies
T
57
What is a benign tumor in chorionic epithelium
hydatiform mole
58
malignancy in choronic epithelium
choriocarcinoma
59
What is largely responsible for the generation of malignant cells?
genetic mutations
60
What are two major categories of mutated genes?
1. oncogenes | 2. tumor suppressor genes
61
What are tumor suppressor genes?
inherent genes that play a role in cell division and DNA repair and are critical for detecting inappropriate cell growth signals
62
What are the categories of carcinogens?
1. viruses 2. radiation 3. chemical
63
cytomegalovirus
kaposi's sarcoma
64
epstein-barr virus
burkitt's lymphoma, immunoblastic lymphoma, nasopharyngeal carcinoma
65
hep B
hepatocellular carcinoma
66
herpesvirus 8
kaposi's sarcoma
67
HIV
kaposi's sarcoma, lymphoma
68
HPV
cervical carcinoma
69
human t cell lymphotropic virus
t-cell lymphomas, hairy cell leukemia