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Flashcards in NMP DUKE midterm Deck (50)
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1

Cerebellum

is folded under the occipital lobe; if opened, you can see the vermis along the midline,
surrounded by the paravermis (intermediate lobe) and the lateral hemisphere/lobe

2

Horizontal fissure

runs along lateral side of the cerebellum

3

Cerebellum specialty

it specializes in coordination of motor activity; it does not initiate or control movement

4

(3) Cerebellum
major regions

1. Archicerebellum (vestibulocerebellum)
2. Paleocerebellum (spinocerebellum)
3. Neocerebellum (corticocerebellum)

5

Vermis

long, narrow, midline structure with many crimps; terminates as the uvula

Primary fissure = deepest fissure of
the vermis

6

Archicerebellum

vermis + paravermis; the middle region; remember the spinocerebellar tracts terminate in the vermis & paravermis (paravermis = intermediate lobe)

7

Neocerebellum

lateral hemispheres/lobes; it develops with
the neocortex

8

Function of Neo + Paleo

coordination of muscles for the purpose of
movement

9

The vermis & paravermis (termination of cerebellar tracts) contain

broken somatotopic map

vermis---Axial skeleton
paravermis---Extremities

10

Two differences of cerebellar somatotopic map
from neocortical somatotopic map

1.Adjacent parts of the body are not perfectly
in line with each other; the representation is topsy
-turvy
2. Body parts may be represented multiple times;
there could be two index fingers, or two forearms; this is because there are many cerebellar tracts entering, each bringing a map , and they don't overlap perfectly

11

cerebellar white matter

arbor vitae

12

Layer 1

molecular layer

13

layer 2

purkinje layer (main cells)

14

layer 3

granular layer

15

Purkinje cells

main neurons of cerebellum
There is one giant dendrite that bifurcates endlessly, but it sends out only one axon,
which terminates on a group of cells deep
in the white matter

16

where do purkinje fibers terminate?

deep cerebellar nuclei

17

What is the arrangement of the entire
cerebellum?

purkinje---->deep cerebellar nuclei----->out of cerebellum

18

Main afferents of the cerebellum

the mossy/parallel fiber system

19

Rosette

cluster of mossy fibers and granule cells together

20

Climbing fibers

cerebellar afferent fibers that don't go to granule cells in rosettes

21

Where do climbing fibers go?

straight to the surface and split to synapse on the purkinjes

22

Where do climbing fibers come from?

climbing fibers are axons from the inferior olive (olivocerebellar fibers)

23

Where do climbing fibers enter the cerebellum?

inferior peduncle

24

T or F
climbing and parallel fibers are excitatory to the purkinjes?

T

25

purkinje firing rate----normal

70 AP/sec

26

purkinje firing rate-----excited

150-200 AP/sec

27

T or F
purkinje cells are excitatory on deep cerebellar nuclei.

F
inhibitory

28

T or F
deep cerebellar nuclei are excitatory on everything outside the cerebellum.

F
inhibitory

29

T or F
If the deep cerebellar nuclei are stimulated by purkinje cells the will inhibit the outside the cerebellum.

F
purkinje inhibit deep cerebellum nuclei which excites the outside through double inhibition

30

Three (3) other important cells of the cerebellum

1. basket
2. stellate
3. golgi