Lab Di 2 test 2 Flashcards Preview

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Flashcards in Lab Di 2 test 2 Deck (42):
1

Cholelithiasis

1. 90% of all gallbladder and duct disease
2. stones or calculi in gallbladder

2

Choledocholithiasis

1. 1 in 10 have this (cholelithiasis already)
2. gallstones in common bile duct
3. gives obstruction to bile flow leading to jaundice and itching

3

cholecystitis

1. acute or chronic inflammation of GB impacting cystic duct
2. acute= middle age
3. chronic = old

4

gallstone ileus

1. are
2. gallstone into intestine causing blockage

5

billary cirrhosis

1. ascending infection of bilary system
2. leads to obstructive jaundice
3. involves portal and periportal system

6

stone analysis
cholesterol
diagnosis

US

7

stone analysis
Bile Pigment Stones
diagnosis

HIDA scan: cystic duct obstruction

8

stone analysis
mixed
diagnosis

echography/xrays

9

Cardiovascular tests
categories

1. MI-lab tests
2. CAD/CHD
3. primary and secondary HTN
4. CHF
5. DVT

10

MI Tests
current

1.CK
2. CKMB (CK2)
3. Troponin
4. Myoglobin (sometimes)

11

Mi Tests
classic

CPK
CPK electro
LDH
LDH electro
SGOT
SGPT

12

Post MI lab tests levels
CK
earliest increase

3-6 hours

13

Post MI lab tests levels
CK
max level

24-36 hours

14

Post MI lab tests levels
CK
return to normal

3 days

15

Post MI lab tests levels
CK
amplitude X normal

7x

16

Post MI lab tests levels
troponin
earliest increase

3- 6 hours....slightly earlier than CK

17

Post MI lab tests levels
troponin
Max level

12-16 hours

18

Post MI lab tests levels
troponin
return to normal

4-9 days

19

Post MI lab tests levels
troponin
Amplitude X normal

-----

20

Post MI lab tests levels
AST
earliest increase

6-8 hours

21

Post MI lab tests levels
AST
Max Level

24-48 hours

22

Post MI lab tests levels
AST
Return to normal

4-6 days

23

Post MI lab tests levels
AST
Amplitude X normal

5x

24

Post MI lab tests levels
LDH
Earliest increase

10-12 hours

25

Post MI lab tests levels
LDH
MAX level

48-72 hours

26

Post MI lab tests levels
LDH
Return to normal

10-12 hours

27

Post MI lab tests levels
LDH
Amplitude X normal

4x

28

CK indications

1. MI
2. Skeletal Muscle disease
3. Neurologic disease

29

Troponin indications

1. chest pain due to cardiac ischemia
2. specific for cardiac muscle injury
3. prediction of future cardiac problems

30

What distinguishes cardiac from skeletal forms of troponin?

ELISA pg 39

31

Troponin clinical implications

1. differentiation btw cardiac and non-cardiac pain
2. evaluation of unstable angina
3. estimation of size of an MI
4. Detection of reperfusion associated with coronary recanalization
5. detection of periperative MI

32

Myoglobin indications

1. early diagnosis of a MI
2. skeletal muscle injury of disease

33

Myoglobin elevation indicates

1. MI
2. skel mm inflammation (myositis)/ ischemia
3. trauma
4. mm dystrophy
5. seizures
6. rhabdomyolysis

34

CAD/CHD
screening

1. Cholesterol
2. Triglyceride
3. HDL
4. Lipoprotein electro
5. Lipid ratio

35

Cholesterol
indications

1. CHD and hyperlipidemia
2. part of a lipid profile

36

Cholesterol
clinical considerations

1. Fasting
2. diet
3. alcohol

37

hypercholesteremia

1. familial
2. hyperlipidemia
3. hypothyroidism
4. DM uncontrolled
5. MI
6. stress
7. atherosclerosis
8. biliary sclerosis

38

Hypocholesteremia

1. malnutrition
2. malabsorption
3. HYPERthyroidism
4. pernicious anemia
5. hemolytic anemia
6. septicemia
7. liver disease

39

increased mortality risk comes with cholesterol levels are greater than

160 mg/dl

40

Lipoproteins

HDL, LDL, VLDL

41

HDL ratio ideal

3:1

42

LDL=

total cholesterol - (HDL+triglyceride/5)