Biology 1.4 Flashcards
(35 cards)
G1 Phase
Increase cytoplasm, protein synthesis, duplication of organelles
S Phase
Synthesis, DNA and centrosomes duplicated and cell continues to grow
G2 Phase
Cell continues to grow and prepares for division
Mitosis
Division of nuclear DNA, PMAT
Cytokinesis
Division of cytoplasm into 2 cells
SA to volume ratio
As cell grows, volume increases faster than SA. Membrane cannot support cell which causes cell division, shape change or apoptosis
Genome to volume ratio
Volume increases as cell grows but genome size remains the same. Genome cannot make enough material to regulate cell activities for the larger cell volume
G1 cell checkpoint
Check cell to see if it is in proper conditions for division such as environment and healthiness of DNA.
G0
Cell enters this phase if it does not pass the G1 cell checkpoint. It stays here until the cell is ready for division
G2 cell checkpoint
Checks if DNA is undamaged and properly replicated
M cell checkpoint
Checks if chromosomes are properly attached to microtubules for proper division of genome
CDK’s (Cyclin-dependent kinases)
When bound by cyclin, CDK’s phosphorylate other enzymes to switch them to their active configuration. These enzymes regulate the cell and can act as checkpoint markers.
Growth Factors
A signalling molecule released by damaged cells that can bind to a membrane receptor of another cell, causing it to undergo division
Density-dependent inhibition
If cells in an area are too dense, they will stop dividing
Anchorage dependence
Cells need to be anchored to a surface to undergo division.
Cytokinesis in plants
Vesicles from Golgi apparatus align at plane of division and fuse to form a cell plate. Cell plate becomes plasma-membrane of daughters. Next, cell wall forms around the 2 cells
Cytokinesis in animals
Microfilaments form a ring along division plate and shorten/tighten which causes the cell to pinch into a cleavage furrow
Prophase
Duplicated chromatin condenses to sister chromatids. Nucleoli disappears and nuclear envelope breaks down. Mitotic spindle forms, centrosomes move to opposite poles and microtubules develop.
Metaphase
Sister chromatids align at metaphase plate and each one is attached to microtubule from opposite poles at their kinetochore.
Anaphase
Microtubules pull each chromosome to opposite poles. Each pole has complete set of chromosomes with same genetic content as original cell
Telophase
Nuclear envelope reappears around each pole, forming 2 separate nuclei. Chromosomes decondense to chromatin and nucleoli appears
Meiosis
In males and females, produces haploid germ cells called sperm and oocytes. Produces genetically distinct germ cells. Starts with interphase followed by meiosis I and meiosis II
Prophase I
Chromatin condenses to chromosomes, nucleolus disappears and spindle apparatus develops. Synapsis, the physical pairing of maternal and paternal homologous chromosomes, occur to form a tetrad/bivalent. Afterwards, synaptonemal complex forms between the homologous chromosomes and crossing over occurs between non-sister chromatids at the crossed chiasmata point
Metaphase I
Tetrads align randomly, called independent assortment at metaphase plate. Microtubules from opposite poles connect at kinetochore of each pair of sister chromatids