Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

PHS 3300 > Blood Disorders pt 2 > Flashcards

Blood Disorders pt 2 Flashcards

(64 cards)

Start Studying
1
Q

hematuria

A

blood in urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is von willebrand disease due to

A

decrease or absence of the von Willebrand factor and decrease in factor 8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is necessary for stabilization of factor 8

A

VWF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are some clinical manifestations of hemophilia

A

bruising
nosebleeds
prolonged bleeding
mouth/gum bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

who would get chronic DIC

A

cancer patients with malignancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what does activated partial thromboplastin time assess

A

the intrinsic pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

do you have high or low platelets in DIC

A

low

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is acute DIC

A

secondary to trauma, ie sepsis, snake bite, or massive hemorrhage and thrombosisw

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

when does Immune thrombocytopenia purpura develop symptoms

A

until youre under 100 000uL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is the main danger of severe platelet deficits

A

intracranial hemorrhage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

hemophilia B is also known as

A

Christmas disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

how can one aquire thrombocytopenia

A

viral infections (among other factors)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what are the 3 main causes of qualitative platelet disorders

A

drugs
systemic inflammatory conditions
hematologic alteration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what does bleeding time evaluate

A

vascular status and platelet function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is a coagulopathy

A

defect of the normal clotting mechanism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what can a prothrombin time test show

A

coagulation defect in the extrinsic pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what is disseminated intravascular coagulation

A

both bleeding and clotting occur simultaenously

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

are aquired or congenital qualitative platelet disorders more common

A

acquired

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what is secondary polycythemia

A

physiologic response due to increased EPO due to chronic hypoxia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what is thrombocytosis

A

high number of platelets in the blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

is it more common for platelet disorders to be acquired or inherited

A

acquired

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

what are the most common forms of thrombocytopenia a result of

A

increased platelet destrcution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what is thrombocytopenia

A

decreased platelet count resulting from decreased platelet production, increased consumption or both

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what are some clinical manifestations of VWD

A

mucous membrane hemmorages
nose/GI bleeding
ecchymosis
menorrhagia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
difference between thrombocythemia and thrombocytopenia
thrombocythemia: high number of platelets thrombocytopenia: low numbers of platelets
26
what is the most common inherited bleeding disorder
hemophilia
27
Ecchymosis
a discoloration of the skin resulting from bleeding underneath,
28
what is hemophilia associated with (chromosome)
sex chromosome X
29
what is DIC triggered by
another medical issue that affects the blood clotting pathway
30
what are the primary cause of bleeding in platelet disorders
abnormality in the quantity or quality of platelets
31
what does primary polycythemia result from
abnormal regulation of the multipotent hematopoietic stem cells
32
is the hemophilia gene recessive or dominant
recessive
33
what does thrombin time reflect
the quality and quantity of fibrinogen
34
are coagulation disorders more common in men or women
men
35
what is polycythemia
abnormally high RBC mass resulting in higher blood viscosity
36
what is hemophilia
a group of hereditary disorders that affect blood clotting
37
what is the activated partial thromboplastin time
time it takes for a sample of plasma to clot after addition of compounds that mimic contact of blood with an artificial surface
38
what are the vitamin-K dependent coagulation factors
2,7,9,10
39
when does petechiae and purpura occur with ITP
when platelets are under 50 000uL
40
what is primary polycythemia
chronic neoplastic, non-malignant condition of overproduction of RBCs independant of EPO
41
menorrhagia
very heavy bleeding on your perido
42
hemophilia A is associated with what factor and is what percent of cases
85% factor 8
43
what are the two forms of polycythemia
relative absolute
44
thrombocytopenia
decrease in number of circulating platelets
45
what are the two forms of absolute polycythemia
primary secondary
46
is it more common for coagulation disorders to be congenital or acquired
congenital
47
when thrombocytopenia is severe, there is considerable risk of what?
visceral hemorrhages
48
what does the D-dimer assay reflect
fibrinolysis
49
what are the 2 kinds of vitamin deficiency
bleeding in infancy acquired
50
thrombocythemia
increase in the number of platelets
51
what is chronic DIC characterized by
subacute hemorrhage diffuse microcirculatory thrombosis
52
is congenital or aquired thrombocytopenia more common
acquired
53
what are some clinical manifestations of vitamin K deficiency bleeding in infants
black feces hematuria umbilical bleeding
54
what is the prothrombin time
time it takes for a sample of plasma to clot after additon of tissue extract
55
thrombocytopenia and thrombocythemia are examples of what kind of disorders
platelet
56
what are some clinical manifestations of aquired vitamin K deficiency
bleeding: mucosal GI menorrhagia hematuria
57
what is thrombin time
the time needed to convert fibrinogen to fibrin
58
what is relative polycythemia
Hct increased due to dec in plasma volume
59
is DIC aquired or congenital
acquired
60
what can thrombocytosis lead to in some patients
thrombosis
61
hemophilia Bis associated with what factor
factor 9
62
detection of what is a widely used test for DIC
D-dimers
63
are platelet disorders more common in men or women
women
64
what is hemostasis
process for stopping of bleeding and preventing blood loss after vessel injury

PHS 3300 (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions