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Flashcards in Breast Physiology Deck (27):
1

Breasts develop from epidermal thickenings known as

milk lines

2

Breast feeding allows for ___ __ of the child and promotes uterine

passive immunity; involution

3

Majority of cancers develop in the

upper outer quadrant

4

Breast lobules are held in place by __ ligaments

cooper's

5

Majority of blood supply to the breast comes from the

internal mammary artery

6

Lymph and arterial drainage is __ to __ and the first sign of breast cancer is in the ___ lymph node

medial to lateral; axillary

7

Milk originates in the ____ unit

terminal duct lobular unit

8

Hormone dependent breast development events include ___ of ducts and parenchymal differentiation into ___

canalization; colostrum

9

Ductal elongation in puberty is driven by

estrogen

10

__ inhibits breast growth in males

testosterone

11

Histologically during adolescence you see more ___ of the ducts

branching

12

The __ phase of the menstrual cycle is the most mitogenic because of both E and P being present- breasts may be more ___ due to ___ during this phase

luteal; sensitive; edema

13

Lobuloalveolar development is driven by which two hormones

progesterone and prolactin

14

__ and ___ inhibit prolactin's lactation effect

progesterone; estrogen

15

__ (NT) inhibits prolaction

dopamine

16

The baby's suckling causes a neural reflex which inhibits ___ and increases __ allows milk flow

dopamine; prolactin

17

__ are not required to sustain laction

ovaries

18

What is the effect of unremoved milk in the ducts?

Increases acinar pressure and leads to apoptosis

19

Ducts and glands are replaced by __ in menopausal women

fat

20

Polythelia is excess

nipples

21

Chest wall deformity and absent pec muscles is known as

poland syndrome

22

____ is excess milk production non-lactating women or women who have stopped breast feeding over 6 months ago. Causes include __ and drugs

Galactorrhea; prolactinoma

23

___'s syndrome is an infarction of the pituitary during pregnancy and women may lack postpartum milk production

Sheehan's

24

__ is overdevelopment of the male breast

gynecomastia

25

There is a __ risk of breast cancer for each year menarche is delayed

decreased

26

The more exposure to __ the more risk of breast cancer

estrogen

27

Late childbirth is an __ risk of breast cancer

increased