Puberty Flashcards

1
Q

Adrenarche is an increase in adrenal androgen production from the __ __ of the adrenal gland

A

zona reticularis

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2
Q

What three hormones are increased

A

DHEA, DHEA-S, androstenedione

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3
Q

Adrenarche is independent of the __ hormone

A

ACTH

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4
Q

Occurs ___ sexual characteristics appear and is responsible for ___

A

before; pubarche

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5
Q

Adrenarche and __ are independently regulated

A

gonadarche

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6
Q

Thelarche (breast development) occurs in response to

A

gonadarche

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7
Q

Thelarche is stimulated by an onset of ___ and ___ secretion

A

GnRH; gonadotropin

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8
Q

Tanner development stages of the breast and pubic hair occurs earlier in __

A

blacks

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9
Q

Pubic and axillary hair development is due to __ only

A

adrenarche

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10
Q

Adrenarche plays little role in

A

skeletal development

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11
Q

Menarche occurs 2 years after

A

breast development

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12
Q

Initial menstrual cycles may be ___ because you don’t reach the ___ levels to get a LH peack

A

anovulatory; estrogen

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13
Q

It’s usual to have __ cycles for 3-4 years after initial menarche

A

irregular

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14
Q

__ girls may have early thelarche especially because adipose tissue has more ___

A

Fat; aromatase

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15
Q

Male puberty changes: sertoli cells stop ___ and the __ testicle grows faster

A

mitosis; right

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16
Q

Growth in girls during puberty is due to __ and __, and is also supported by __ for bone closing

A

GH and IGF-1; estrogen

17
Q

The __ extremities grow before the __, and the _ grow before the __

A

distal; proximal; legs; trunk

18
Q

Girls have their peak growth spurt __ years before boys

A

2

19
Q

Because ___ levels are high during the neonatal period, high levels of __ can lead to estrogen or testosterone and form ___ __

A

gonadotropin; fsh; ovarian cysts

20
Q

During childhood, something central suppresses the ___

A

HPG axis, FSH, LH

21
Q

__ is a prepuberty marker of GnRH

A

LH

22
Q

An initial sign of puberty is a nighttime surge of

A

LH

23
Q

_ testosterone is needed for sperm production

A

local

24
Q

__ NT may inhibit GnRH

A

GABA

25
Q

Increased ___ may be associated with delayed puberty

A

NPY

26
Q

__ is the hormone product of the ob gene and regulates __ and __ maturation

A

leptin; appetite; sexual

27
Q

Leptin doesn’t provide the signal which starts the pulsatile release of

A

GnRH

28
Q

Another key hormone is ___ in the starting of the GnRH release

A

kisspeptin

29
Q

___ status is probably the most important factor in starting menarche

A

nutritional

30
Q

Exposure to __ may cause early puberty, same with diethylhexyphenatle

A

BPA

31
Q

Environmental factors may act on transcription through

A

epigenetics