Genetic Breast Cancer Flashcards Preview

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Flashcards in Genetic Breast Cancer Deck (11):
1

The single most dietary factor for breast cancer is

alcohol

2

The mutation is the __ gene trumps any minor risk factors for the individual but minor risk factors like ___ are more important at the population level

BRCA; obesity

3

Breast cancers have less __ components and are more sporadic

hereditary

4

BRCA genes code for ____ ___ and need a loss of __ to be deletrious

tumor suppressors; heterozygosity

5

BRCA2 is implicated in causing other cancers with the exception of ___ cancer, which BRCA1 is more associated with

ovarian

6

__ jews should be tested for breast cancer gene

Ashkenazi

7

The ___ procedure reduces the risk of both breast and ovarian cancer

salpingo-oophorectomy

8

BRCA genes repair

DS DNA breaks

9

PARP inhibitors cause __ in cells

DS DNA breaks

10

Patients who have relatives with breast cancer and are ___ __ should undergo the same breast cancer screenings as the population

true negatives

11

CDH1 mutations are associated with __ cancer

gastric