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Step One R&M > Cancer associations, paraneoplastic syndromes > Flashcards

Cancer associations, paraneoplastic syndromes Flashcards

(55 cards)

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1
Q

CCl4

A

Centrilobular necrosis and fatty change of the liver

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1
Q

2nd leading cause of lung cancer

A

Radon

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1
Q

Antibodies against presynaptic Ca<span>2+</span> channels

A

Lambert-Eaton

Small cell carcinoma

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2
Q

EPO production

A
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2
Q

HPV

A

Cervical and penile cancer (16,18)

Throat or head and neck cancer

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3
Q

HHV-8

A

Kaposi sarcoma, body cavity fluid B cell lymphoma

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4
Q

XP, albinism

A

Melanoma, BCC, and especially squamous cell carcinoma of the skin

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6
Q

Aromatic amides

A

Transitional cell carcinoma

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6
Q

Cigarette smoke: lung

A

Squamous and small cell

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7
Q

Down syndrome

A

ALL, AML

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7
Q

Hypercalcemia

A

Squamous cell carcinoma (PTHrp)

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8
Q

Vinyl chloride

A

Angiosarcoma of liver

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9
Q

Barret esophagus

A

Adenocarcinoma of esophagus

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10
Q

Arsenic

A

Liver: Angiosarcoma

Lung: Lung cancer

Skin: Squamous cell carcinoma

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11
Q

Cushing syndrome

A

Small cell lung cancer

Increased ACTH

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12
Q

Autoimmune diseases

A

Lymphoma

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12
Q

Chronic atrophic gastritis, pernicious anemia, postsurgical gastric remnants

A

Gastric adenocarcinoma

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13
Q

HBV, HCV

A

HCC

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15
Q

Actinic keratosis

A

SCC of skin

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16
Q

Dermatomyositis

A

Lung cancer

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16
Q

Paget disease of bone

A

Secondary osteosarcoma and fibrosarcoma

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17
Q

Cigarette smoke: bladder

A

Transitional cell

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17
Q

Hypercalcemia

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A

Lymphoma, usually Hodgkin’s

Increased vitamin D

18
Q

AIDS

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A

Non-Hodgkins lymphoma, Kaposi sarcoma

19
Cigarette smoke: kidney
Renal cell carcinoma
21
Cirrhosis
HCC
23
UC
Colonic adenocarcinoma
24
MG, pure RBC aplasia
Thymoma
25
Cushing syndrome
Small cell lung cancer
26
Cigarette smoke: pancreas
Pancreatic adenocarcinoma
27
Ionizing radiation: thyroid
Papillary carcinoma of the thyroid
27
EBV
Burkitt lymphoma, nasopharyngeal carcinoma, CNS lymphoma, Hodgkin lymphoma
28
Where do alfatoxins come from?
Aspergillus
30
SIADH
Small cell lung cancer
32
Polycythemia
Renal cell carcinoma, HCC
34
Immunodeficiency states
Lymphomas
36
Asbestos
Bronchogenic carcinoma \> mesothelioma
37
Dysplastic nevus
Melanoma
38
Radiation exposure
Leukemia, sarcoma, breast cancer, papillary thyroid cancer
38
Cigarette smoke: larynx
Squamous cell carcinoma
39
H. pylori
Gastric adenocarcinoma, MALToma
41
Radon
Lung cancer
42
PTHrP
Squamous cell carcinoma of the lung, renal cell carcinoma, breast cancer Hypercalcemia
43
Lambert-Eaton syndrome
Small cell cancer
45
Acanthosis nigricans
Visceral malignancy, esp stomach
46
Plummer-Vinson syndrome
Squamous carcinoma of esophagus (PVS = dysphagia + glossitis + iron-deficiency anemia)
47
Alkylating agents
Leukemias, lymphoma
48
Increased ADH
Small cell lung cancer or intracranial tumors SIADH
49
Patient with MG has high hematocrit. Why?
Has a thymoma that's producing EPO
50
Tuberous sclerosis
Giant cell astrocytoma, renal cell angiomyolipoma, cardiac rhabdomyoma
51
Nitrosamines
Gastric cancer
52
Schistosoma haematobium
Squamous cell bladder cancer
53
Aflatoxin
HCC
54
HTLV-1
Adult T-cell lymphoma/leukemia
55
Cigarette smoke: esophagus
Squamous cell/adenocarcinoma

Step One R&M (38 decks)

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