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Flashcards in Virus stuff Deck (59):
1

Anti-HBs + Anti-HBe + Anti-HBc IgG

Recovery

2

Immunized to HBV serum

Anti-HBs

3

DNA hepatitis virus

Hep B

 

(All others are RNA)

3

Where does CMV stay latent?

Mononuclear cells

3

Chronic phase serum with low infectivity

HBsAG

Anti-HBe

Anti-HBc IgG

4

Which DNA viruses are not linear?

Papilloma

Polyoma

Hepadna

4

Which DNA virus does not replicate in the nucleus nor has an icosahedral capsid?

Pox virus

 

 

(remember it's the largest virus = can carry its own DNA-dep RNA polymerase)

4

Owl eye inclusions

CMV

4

Waterborne epidemics, hepatitis

HEV

5

Requires another virus

HDV requires HBV

7

HBsAG + Anti-HBe + Anti-HBc IgG

Chronic infection with low infectivity

8

Roseola infanatum

8

Fecal-oral hepatitis viruses

HAV

HEV

8

How do anti-HBV antibodies protect against hepatocellular damage?

Antibodies prevent viral entry into cells, so antigens can never be loaded onto MHC class I and presented to CD8+

9

Hepatits that's usually asymptomatic

HAV

9

DNA hepadnavirus

HBV

10

Worse prognosis HDV

Co-infection with HBV

12

ssDNA virus

Parvovirus

12

Measles

13

Chronic HBV serum with high infectivity

HBsAg

HBeAg

Anti-HBc IgG

14

Anti-HBe + Anti-HBc IGM

Window period (5-6 months after infection)

15

High fevers for several days that can cause seizures followed by a maculopapular rash

Roseola (HHV-6)

17

Which virus gets its envelope from the nuclear membrane?

Herpesviruses

 

(All other enveloped virus get it from cytoplasmic membrane)

18

19

Better or worse prognosis? HDV after HBV

Better (Superinfection better than co-infection)

20

Acute phase serum HBV

HBsAg

HBeAg

Anti-HBc IgM

21

Hepatitis with short incubation

HAV

HEV

22

dsRNA virus

Reoviridae (Coltivirus, Rotavirus)

23

Replicate in nucleus

DNA viruses (except pox virus)

Flu

Retroviruses

23

High mortality in preggos, hepatitis

HEV

24

Which DNA virus is not ds?

Parvovirus

25

Where do DNA viruses replicate?

Nucleus

 

(Except pox virus, which has its own polymerase)

27

DNA viruses

Herpesvirus

Polyomavirus

Papillomavirus

Hepadnavirus

Poxvirus

Parvovirus

Adenovirus

29

Maternal-fetal hepatitis viruses

HBV

HDV

30

HBsAG + HBeAG + HBcAG IgM

Acute phase serum

(1-5 months after infection)

31

Most segmented viruses

Reoviruses (rotovirus, coltivirus) ith 10-12 segments

32

RNA flavivirus (hepatitis)

HCV

34

No carrier state, hepatitis

HAV

HEV

35

Where do RNA viruses replicate?

Cytoplasm (except flu and retroviruses)

36

Roseola (HHV-6)

37

RNA hepavirus

HEV

38

Hepatitis virus that increases HCC risk due to chronic inflammation

HCV

40

Monospot negative mononucleosis

CMV

41

Least segmented virus

Arenavirus (LCMV, lassa fever encephalitis)

43

Rubella

44

Hepatitis virus that increases HCC risk by incorporating into genome and acting as an oncogene

HBV

45

Kaposi sarcoma is a neoplasm of ____

Endothelial cells

46

Window period serum HBV

Anti-HBe

Anti-HBc IgM

47

No HCC risk, hepatitis

HAV

HEV

48

HBsAg + HBeAg + Anti-HBc IgG

Chronic infection with high infectivity

50

Which naked nucleic acid particles would not be infectious?

dsRNA (Coltivirus, Rotavirus)

- ssRNA (Orthomyxoviruses, Paramyxoviruses, Rabies, Ebola, LCMV, Bunyaviridae, Hep D)

 

 

**These viruses carry their own polymerases so require in tact virions**

51

Cause of Roseola?

HHV-6

52

A person has anti-HBs in their blood but no anti-HBc. What do you know about this patient?

Was vaccinated

53

Unenveloped viruses

Adenovirus

Polyoma virus

 

54

Which RNA viruses don't replicate in the cytoplasm?

Flu, retroviruses

56

RNA picornavirus (hepatitis)

HAV

57

Congenital rubella

 

(Blueberry muffin spots = extramedullary hematopoeisis)

58

Segmented viruses

All are RNA viruses:

Bunyavirdae

Orthomyxovirus (flu)

Arenavirus (LCMV, Lassa fever)

Reovirus (rotavirus, coltivirus)

59

Recovery phase serum HBV

Anti-HBs

Anti-HBc IgG