Pharm equations Flashcards
1
Q
Low Vd
A
Blood; large/charged and/or protein-bound molecules
2
Q
Maintenance dose =
A
Cp x CL x dose interval/F
3
Q
Loading dose =
A
CP x Vd/F
4
Q
CL =
A
Rate of elimination/plasma concentration
5
Q
High Vd
A
All tissues including fat; small lipophilic molecules, especially if bound to tissue protein
6
Q
T1/2=
A
0.693xVd/CL
7
Q
Vd=
A
amount of drug in the body/amount of blood in the plasma
8
Q
Medium Vd
A
ECF, small hydrophilic molecules
