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Flashcards in Drug thangs Deck (38):
1

Omalizumab

IgE

 

Prevents IgE from binding to its receptor

 

Allergic asthma

2

Cetuximab

EGFR

 

Stage IV CRC, head and neck cancer

2

RANKL mab

Denosumab

4

Prevents IgE binding to its receptor

Omalizimuab

4

MAB that inhibits neutrophil adhesion

Natalizumab (alpha4-integrin)

6

Avoid in pregnancy due to gray baby syndrome

Chloramphenicol

7

Avoid in pregnancy due to kernicterus

Sulfas (severe jaundice)

8

Avoid in pregnancy due to dicolored teeth/bones

Tetracyclines

9

Natalizumab

Alpha4-integrin

 

MS, Chron's

 

Increased risk of PML

10

Infliximab

TNFalpha

 

IBD/RA/ankylosing spondylitis/psoriasis

10

RSF F protein mab

Palivizumab

11

HER2/neu mab

Trastuzumab

12

MAB that can causes PML

Natalizumab

13

Antidote that is a mab

Digoxin immune Fab

14

Avoid in pregnancy due to teratogenic effects

Griseofulvin

Ribavirin

14

CD20 mab

Rituximab

15

Avoid in pregnancy due to ototoxicity

Aminoglycosides

15

Palivizumab

RSV F protein

 

Prevents RSV in high-risk infants

16

EGFR mab

Cetuximab

17

MAB for CLL

Alemtuzumab (CD52)

19

CD52 mab

Alemtuzumab

21

Bevacizumab

VEGF

 

CRC, renal cell carcinoma

22

MAB for osteoporosis

Denosumab (RANKL)

23

GpIIb/IIIa mab

Abciximab

24

Trastuzumab

HER2/neu

 

Breast CA, gastric CA

24

Adalimumab

CD20

 

RA/IBD/ankylosing spondylitis/psoriasis

25

Avoid in pregnancy due to embryotoxic effects

Clarithromycin

27

Abciximab

GpIIb/IIIa

 

Prevents fibrinogen binding = no platelet aggregation

 

Prevention of ischemia in patients undergoing coronary interventions

28

Patient with MS or Chron's develops rapidly progressive neuro signs

Think natalizumab = increased risk of PML

29

Alemtuzumab

CD52

 

CLL

(aLYMtuzumab)

30

TNFalpha mab

Infliximab

Adalimumab

31

Avoid in pregnancy due to cartilage damage

Fluoroquinolones

32

8 antibiotics to avoid in pregnancy

Sulfas

Aminoglycosides

Chloramphenicol

Griseofulvin

Ribavirin

Tetracyclines

Clarithromycin

Fluoroquinolones

34

VEGF mab

Bevacizumab

35

IgE mab

Omalizumab

36

Denosumab

RANKL

 

Inhibits osteoclast activation

 

Osteoporosis

37

Alpha4-integrin mab

Natalizumab

38

Rituximab

CD20

 

RA (+ MTX), B cell lymphoma, ITP