Chapter 10: Micromineral (Iodine) Flashcards

(34 cards)

1
Q

required as a component of thyroid hormone, thyroxine (t4) and triiodothyronine (t3)

A

iodine

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2
Q

2 thyroid hormones

A

thyroxine; triiodothyronine

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3
Q

thyroid hormone (t4)

A

thyroxine

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4
Q

thyroid hormone (t3)

A

triiodothyronine

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5
Q

dietary iodine is in the form of

A

iodide

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6
Q

iodine - functions

a part of the _____

essential in regulating body’s growth, development, and metabolic rate

A

thyroid hormone

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7
Q

iodine - functions

_____ and _____ are required for normal energy metabolism, thermoregulation, and intermediary metabolism

A

thyroxine and triiodothyronine

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8
Q

iodine - functions

essential in the conversion of _____ to vitamin a

A

carotene

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9
Q

iodine - functions

protein synthesis, carbohydrate production, rbc production, nerve muscle function

A

-

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10
Q

iodine - absorption and metabolism

iodine is absorbed mainly in the _____, distributed in the extracellular fluids

A

small intestine

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11
Q

iodine - absorption and metabolism

reduced first to the absorbable _____; absorbed iodide is converted to iodine before it enters the circulatory system

A

iodide

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12
Q

iodine - absorption and metabolism

1/3 of the absorbed iodide in the blood is taken up by the _____ for synthesis of the thyroid hormones thyroxine (t4) and triiodothyronine (t3)

A

thyroid gland

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13
Q

iodine - absorption and metabolism

t3 and t4 circulate in the bloodstream bound to thyroxine binding globulin, prealbumin, and albumin

_____ is biologically more potent than _____

A

t3; t4

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14
Q

iodine - absorption and metabolism

the release of the t3/t4 by the thyroid is usually at a ratio of _____

this ratio is decreased when there is lack of iodine

A

20/1

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15
Q

iodine - absorption and metabolism

the rest of the iodide is excreted in the _____, some amounts are lost via the skin and feces

A

urine

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16
Q

iodine - absorption and metabolism

the metabolism of iodine occurs under the _____

A

hormonal feedback control

17
Q

iodine - absorption and metabolism

the uptake, synthesis, and release of iodine by the thyroid gland is stimulated by _____ released by the anterior pituitary gland

A

thyroid stimulating hormone

18
Q

iodine - interrelationship with other nutrients

from cabbage, kale, cauliflower, broccoli, turnip, brussel sprouts, and mustard greens

are substances that interferes with iodine metabolism inhibiting hormogenesis

19
Q

iodine - interrelationship with other nutrients

the goitrogens that affect iodide uptake by the thyroid glans, organification of the iodide or hormone release from the thyroid cells:

halide ions: bromide (br)
astatide (at-)
thiocyanate (SCN-)

20
Q

iodine - interrelationship with other nutrients

cassava contains _____ with thiocyanates as metabolites

A

cyanogen glucosides

21
Q

iodine - food sources

iodized salt, seafoods, seaweeds

22
Q

iodine - deficiency

most common forms of iodine deficiency are: _____ and _____

A

endemic goiter and cretinism

23
Q

iodine - deficiency

lack of iodine results in an enlargement of the _____ (goiter)

A

thyroid gland

24
Q

iodine - deficiency

enlargement of thyroid gland is due to over stimulation of the thyroid by _____ and _____, which are present in increased levels in an attempt to produce more circulating t3 and t3

A

TRF and TSH
thyrotropin-releasing factor;
thyroid-stimulating hormone

25
iodine - deficiency developmental defect in infants characterized by a dry thick skin, puffy face, and eyelids, enlarge tongue, husky voice, decreased reproductive ability, and mental retardation
cretinism
26
iodine - toxicity also known as Grave's disease or exophthalmic goiter increased basal metabolism, goiter, and disturbances in the autonomic nervous systems causing hyper irritability and increased creatinine metabolism
hyperthyroidism
27
hyperthyroidism is also known as
grave's disease or exophthalmic goiter
27
iodine - deficiency severe iodine deficiency can produce _____ which is characterized by a dry, waxy type swelling, with abnormal deposits of mucoproteins under the skin
myxedema
28
iodine - recommended intake for infants to children (0-5 years old) both male and female
90 ug
29
iodine - recommended intake for children (6-12 years old) both male and female
120 ug
30
iodine - recommended intake for children and adults (13->70 years old) both male and female
150 ug
31
iodine - recommended intake for pregnant and lactating
150 +100
32
iodine - recommended intake the recommended intake for adult corresponds to the intake necessary to maintain _____ level above the critical limit likely to be associated with the onset of goiter it corresponds to the daily iodine urinary excretion of _____ ug/L
plasma iodide; 100 ug/L
33
pregnant and lactating mothers
at risk of developing iodine deficiency