chapter 8 Flashcards

1
Q

antioxidants

A

vitamins C,E,A
beta carotene
selenium

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2
Q

a highly unstable atom with an unpaired electron

Highly reactive and can cause damage to molecules in the cell

A

free radical

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3
Q
Unstable free radicals try to steal electrons from surrounding molecules, causing damage to: 
\_\_\_\_\_\_ & \_\_\_\_\_\_\_
disrupts transport in and out of cells
alters \_\_\_\_\_ function
inflammation and blood clots --> \_\_\_\_\_
genetic material
faulty protein synthesis
cell mutation and cell death
A

LDLs & cell protein
cell
CVD

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4
Q
antioxidants function in diff ways:
some vitamins donate their electrons to:
convert \_\_\_\_\_\_ to less harmful substances
break down \_\_\_\_ free radicals
\_\_\_\_\_\_ Stabilize free radicals
A

free radicals
oxidized
phytochemicals

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5
Q

fat soluble vitamin: 2 forms
______ -
______ - 4 biologically active forms (alpha, beta, gamma, delta)
___ most common

A

vitamin E
tocotrienol
tocopherol
alpha

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6
Q
primary role of vitamin E =
serves as an \_\_\_\_\_\_\_\_(donates electron)
stored in \_\_\_\_\_\_\_ and \_\_\_\_\_\_:
protects PUFAs and cell membranes from \_\_\_\_\_\_\_
protects \_\_\_\_\_\_ and lung tissue
protects \_\_\_\_
decreases \_\_\_\_ disease risk
fetal and early childhood development of nerves and muscles
enhances immune system
sources: vegetable oils, nuts, seeds, wheat germ, soybeans, oil based spreads, and dressings
\_\_\_\_ sources are poor
destroyed by \_\_\_\_\_ and \_\_\_\_
A
antioxidant
adipose tissue
cell membranes
oxidation
RBCs
LDLs
heart
animal
oxygen, heat
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7
Q

water soluble vitamin
_____ acid
essential - must be consumed in human diet
antioxidant
Extracellular fluid, donates _____
Protects LDL cholesterol from ______– decrease CVD risk
_____ – imp. For smokers
WBC - immune system
Synthesis of ______ (scurvy), DNA, bile, neurotransmitters, hormones
Enhances the absorption of ___ ** exam

A
vitamin C
ascorbic 
electron
oxidation
lungs
collagen
iron
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8
Q

smokers need an extra ____ mg/day of vitamin C

sources: citrus and more fruit and veggies, fortified beverages and cereal
destroyed by ____ and ____
especially _____
steam, microwave, stir fry

A

35
heat, oxygen
boiling

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9
Q

not enough vitamin C?
____ : bleeding gums, lose teeth, wounds that do not heal, swollen ankles, blah bah
role in production of collagen

A

scurvy

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10
Q

In the class of chemicals called carotenoids – fat-soluble plant pigment found in orange, red, deep yellow fruits and vegetables
_____: inactive form of a vitamin that the body can convert to active form
the precursor of _____

A

beta carotene\
provitamin
retionol (vitamin A)

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11
Q

too much vitamin E?
can interfere w _____ meds (aspirin and coumadin)
may increase risk for ______ stroke
not enough vitamin E?
uncommon, stored in _____ tissue
can result in fragile _____ (erythrocite hemolysis)
____ and associated symptoms

A
anticoagulant
hemorrhagic
adipose
RBC
anemia
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12
Q

too much vitamin C?
megadoses (10x RDA or more) can cause nausea, diarrhea, nosebleeds and abdominal cramps
usually temporary - easily excred in ____
can cause ___ toxicity in people w hemochromatosis
can lead to _____ formation in people with kidney disease
-may act as a ____

A

urine
iron
kidney stone
prooxidant

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13
Q
functions of beta carotene
weak \_\_\_\_\_
\_\_\_ soluble - prevents odixations of LDL and cell membranes
also enhance the immune system
protect skin from \_\_\_
protect \_\_\_ from damage
decrease \_\_\_ risk
sources:
tomatoes - \_\_\_\_\_
greens - \_\_\_\_
added for color
absorbed more from \_\_\_\_\_ foods
A
antioxidant
fat
UV
eyes
cancer
lycopene
lutein
lightly cooked
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14
Q

too much beta carotene?
large quantities do not appear to be toxic
___ may turn yellow/orange at high intakes(reversible)
no known deficiency

A

skin

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15
Q

fat soluble vitamin
excess is stored in the ___ (90%), adipose tissue, kidneys and lungs
three active forms of vitamin A
____: vision, sexual reproduction, bone health immune health
_____: vision, sex repro, bone health, immune health
______: cell differentiation, bone health, immune function
functions
- antioxidant, protecting LDL cholesterol
-essential to proper ____
-___________: the process by which cells mature and specialize
sperm production and fertilization
bone growth

A
lungs
retinol
retinal 
retinoic acid
vision
cell differentation
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16
Q
too much vitamin A? 
-highly toxic, especially from \_\_\_\_\_
birth defects, \_\_\_\_\_\_ abortion
fatigue, loss of appetite, blurred vision, hair loss, skin disorders, bone and joint pain etc
permanent \_\_\_\_ and \_\_\_ Damage
not enough vitamin  A?
\_\_\_\_ blindness in early stages
\_\_\_\_\_\_\_: irreversible blindness
due to lack of \_\_\_, hardening of cornea
immune + reproductive problems
growth failure
A
supplements
spontaneous
liver, eye
night
xerophalmia
17
Q

trace mineral found in few amino acids
functions:
antioxidant
production of ____ a thyroid hormone (basal metabolism)
____: a compound needed for proper functioning of an enzyme
iron, copper, zinc, manganese are cofactors

A

selenium
thyroxine
cofactor

18
Q

a group of related diseases characterized by cells growing out of control

A

cancer

19
Q

cancer development

A

initiation
promotion
metastasize