Circadian Rhythms Flashcards

0
Q

Where do sympathetic neurones arise from?

A

Spinal cord

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1
Q

Where do parasympathetic neurones arise from?

A

The brainstems cranal nerve

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2
Q

What are the features of the enteric nervous system?

A

Work autonomously but can receive parasympathetic and sympathetic innervation, consists mainly of myenteric plexus.

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3
Q

What three properties must circadian rhythms have?

A

Repeat at least once per day, persist in the absence of external cues, adjust to local time

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4
Q

Where in the brain are circadian rhythms controlled?

A

The suprachiasmatic nucleus- above the optic chiasm in the thalamus.

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5
Q

What is the pathway of sleeps circadian rhythm?

A

Photoreceptors to retinal ganglion cells to the hypothalamus, to the intermediolateral cell column, up the superiors cervical ganglion to the pineal gland and melatonin.

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6
Q

What six things are controlled by circadian rhythms?

A

Sleep, alertness, cortisol, growth hormone, temperature and potassium

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7
Q

How does frequency and amplitude change throughout the sleep stages?

A

Awake until stage 4, then frequency decreases and amplitude increases

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8
Q

What waves are used for:

a) awake and active
b) awake
c) 1,2 and 3
d) 4?

A

a) alpha
b) beta
c) theta
d) delta

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9
Q

Hat decreases during non-REM sleep?

A

Physiological function

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10
Q

Which REM or non-REM sleep is deeper?

A

Non-REM sleep, stage 4

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11
Q

Why do we sleep?

A

For ecological, metabolic and learning reasons.

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12
Q

What is the hypothalamus directly linked to and why?

A

The pituitary gland, as it controls the release of many hormones

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13
Q

Give the two types of neuroserectory cells of the pituitary gland?

A

Mangocellular and parvocellular

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14
Q

What are the differences between magnocellular and parvocellular?

A

Magnocellular- are bigger, the hormones are released directly into the bloodstream and the axons project into the posterior lobe

Parvocellular- axons project into the anterior lobe and the hormones are released in two stages.

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15
Q

Give and example of a magnocellular?

A

ADH- when blood pressure is low renin is secreted to convert angiotensin to angiotensin 1 and then 2.

16
Q

Give and example of a parvocellular?

A

Cortisol- ACTH is released to cause direct cortisol release from the adrenal gland.

17
Q

How is alertness controlled?

A

By an ascending reticular activating system

18
Q

What do brain stem lesions lead to?

A

Sleep and coma

19
Q

What does EEG stimulation cause?

A

Non-REM sleep to alert/awake form

20
Q

What neural systems are activated during wakefulness?

A

Noradrenaline, serotonin and histamine.

21
Q

What activity do cholinergic neurones in pons/midbrain border have: a) during waking and REM sleep and b) during non-REM sleep?

A

A) high

B) inactive

22
Q

What effect thalamo-cortical projections and cause them to be more polarised?

A

Cholinergic, serotninergic and neuroadrenergic projections

23
Q

What do EEGs measure?

A

Neural (electrical) activity

24
Q

What are the six stages of sleep?

A

Awake, 1, 2, 3, 4 and REM

25
Q

What is the hypothalamic pituitary axis important for?

A

Temperature control, blood pressure and hunger/satiety

25
Q

What is the hypothalamic pituitary responsible for?

A

The control of secretion of many hormones

26
Q

What is the enteric nervous system?

A

A subdivision of the autonomic NS

27
Q

What does the enteric NS do?

A

Works autonomously to control the activity of the GI tract