Co-existing diseases- Neuromuscular diseases Flashcards by B -

Q

Muscular Dystrophy:

is it hereditary

A

yes

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy:

what is the hallmark description

A

painless degeneration and atrophy of skeletal muscle (associated w/ mental retardation)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy:

what are the characteristics of Pseudohypertrophic muscular dystrophy?

A

CHF
Recurrent PNE
kyphoscoliosis
Hyperkalemia w/ SCh
Malignant hyperthermia suceptibility

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy:

Limb-Girdle muscular dystrophy characteristics

A

relatively benign

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy:

facioscapulahumeral, is the heart involved?

A

nope

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy:

2 characteristics associated with Nemaline Rod Muscuar Dystrophy

A

Micrognathia

Bulbar palsy

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy:

what is the most common and most severe of all the MDs

A

Duchenne’s

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy: Duchenne’s

it is ___-linked ______

A

X-linked recessive

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy: Duchenne’s

when is the onset

A

early childhood

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy: Duchenne’s

are kyphoscoliosis and hip and knee contractors common

A

yes

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy: Duchenne’s

what EKG changes occur

A

prolonged PR and QRS
ST segment abnormalities
BBB
Q waves
Tall R waves

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy: Duchenne’s

what happens to total lung capacity and residual volume

A

reduced

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy: Duchenne’s

they are prone to recurrent what?

A

Pulmonary infection

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy: Duchenne’s

why do u avoid SCh

A

increased risk of MH

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Muscular Dystrophy: Duchenne’s

is Neuromuscular monitoring mandatory?

A

yes

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Multiple Sclerosis:

it is characterized by what?

Study These Flashcards

A

random and multiple sites on demyelination of the corticospinal tract neurons in the brain and spinal cord, exclusive of peripheral neurons

Q

Multiple Sclerosis:

S/S

Study These Flashcards

A

Visual disturbances
Ataxia
Limb Paresthesia and weakness
Spastic paresis of skeletal muscle
exacerbations and remissions

Q

Multiple Sclerosis:

what do you really want to avoid in these pt’s

Study These Flashcards

A

marked temp changes

Q

Multiple Sclerosis:

also avoid what (bc it can exacerbate the symptoms)

Study These Flashcards

A

stress

Q

Multiple Sclerosis:

what can occur w/ SCh

Study These Flashcards

A

hyperkalemia

Q

Multiple Sclerosis:

can u do a spinal

Study These Flashcards

A

questionable (but usually no)

Q

Myasthenia Gravis:

is a chronic autoimmune disease inolving what?

Study These Flashcards

A

the NMJ

Q

Myasthenia Gravis:
it is characterized by weakness and rapid exhuastion of skeletal muscle with repetitive use; is there recovery with rest?

Study These Flashcards

A

yes some recovery

Q

Myasthenia Gravis:

S/S eyes

Study These Flashcards

A

ptosis
Diplopia
(most common initial sign)

Myasthenia Gravis | why is there an increased risk of aspiration

weakness of pharyngeal and laryngeal muscles

Myasthenia Gravis: | is atrophy present?

no- there is asymmetric extremity skeletal muscle weakness

Myasthenia Gravis: | Complication r/t heart

Cardiomyopathy

Myasthenia Gravis: | any thyroid problems

hypothyroidism

Myasthenia Gravis: | treatments

Thymectomy Plasmapheresis Anti cholinesterase drugs Corticosteroids

Myasthenia Gravis: Anesthesia | what would u want to avoid preop

opiods

Myasthenia Gravis: Anesthesia | what would you want to tell the pt (warn them about) in the prep period

poss mechanical ventilation postop

Myasthenia Gravis: Anesthesia | what should you do on induction?

short active IV drugs | Tracheal intubation without muscle relaxant

Parkinson's Disease: | is degenerative disease of the CNS characterized by loss of ________ fibers in the basal ganglia of the brain

dopaminergic

Parkinson's Disease: | _______ is an inhibitory neurotransmitter acting on the extrapyramidal motor system

dopamine

Parkinson's Disease: | S/S

Skeletal muscle rigidity Resting tremor Diaphragmatic spasms Mental depression

Parkinson's Disease: | treatment are drugs times to do what?

increase the concentration of dopamine

Parkinson's Disease: | a common drug these pts are on

levodopa

Parkinson's Disease: | what do you want to avoid during anesthesia

drugs that w/ antidopaminergic effects Droperidol reglan