Peripheral Nervous System "SNS) Flashcards Preview

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Flashcards in Peripheral Nervous System "SNS) Deck (44)
1

The Peripheral Nervous system has 2 divisions what are they?

somatic
Autonomic

2

the somatic nervous system sends Motor (efferent) impulses to where?

Skeletal muscle
(does not have a junction as the Autonomic does)

3

The autonomic nervous system has 2 divisions. what are they?

Sympathetic nervous system (SNS)
Parasympathetic Nervous System (PNS)

4

Sympathetic PREganglionic nerves generally have _____ lengths. While sympathetic POSTganglionic neurons have ______ lengths

short lengths (preganglionic)
Long Lengths ( post ganglionic)

5

Parasympathetis PREganglionic nerves generally have ______ lengths. While Parasympathetic POSTganglionic neurons have _____ lengths.

Long lengths (preganglionic)
Short Lengths (postganglionic)

6

What is the predominant NT in the periphery

ACh

7

the Autonomic division is also termed the what division?

Visceral Efferent division

8

what is a ganglion

A peripheral collection of nerve cell bodies

9

how can you tell the autonomic division vs the somatic division

the autonomic division has an interruption

10

is the peripheral nervous system protected by bones?

no

11

explain the Parasympathetic Nervous system
include Pre and post ganglion fiber, and NT

Long preganglionic
Short Postgangionic
preganglionic and Postgangliionic NT ACH
Cholinergic fibers

12

What type of fibers are the PNS?

Cholinergic

13

explain the sympathetic Nervous system
include Pre and post ganglion fiber, and NT

Short pre
Long post
Pre NT ACh
Post NT NE
Adrenergic Fibers

14

What type of fibers are the SNS

Adrenergic

15

what part of the Autonomic division is the odd ball and why?

Adrenal Medulla
b/c it has to Post ganglionic, the preganglionic fiber goes directly to adrenal medulla and releases ACh then the adrenal medulla releases hormones epi and NE

16

what does the somatic divisions nerve fiber look like?

1 long uninterrupted neuron
from cord to skeletal muscle

17

What NT does the Somatic division release at the nerve terminal?

ACh

18

What receptors are found on tissues innervated by the PNS

Muscarinic

19

What receptors are found at the autonomic ganglion on the cells of the adrenal medulla and motor end-plate of skeletal muscle?

Nicotinic

20

receptors can be what 2 types?

ion channels (open)
G-protein coupled (2nd messengers)

21

What type of receptor is the nicotinic

Ion channel

22

What type of receptor is the muscarinic

G -protein

23

How would you know if it is a muscarinic receptor?

it's at the tissue

24

see page 32 of sweat book to see the receptor sites

look at muscarinic and nicotinic

25

what is the other name for the SNS

thoracolumbar

26

The SNS or thoracolumbar system outflow arises from what segments

T-1 to L2 (or L3)

27

Most sympathetic PREganglionic neurons synapse with the POSTganglionic fibers where?

paravertebral ganglion (side note.. this is right next to the spinal cord thus the reason for SNS has a Short preganglionic and long post

28

the Sympathetic cardiac accelerators arise from where?

T1-T4

29

The stellate ganglion is formed by what?

the inferior cervical and first thoracic ganglion

30

tell me 3 ways to know that it is the SNS

Short pre
Long post
Arise from thoracic or lumbar

31

In The SNS or thoracolumbar system all PREganglionic fibers pass through what?

white rami

32

In The SNS or thoracolumbar system some not all POSTganglionic fibers pass through what

Gray ramus

33

When presynaptic alpha-2 receptors are stimulated by NE or any other drug with alpa-2 receptor agonist activity, the synthesis and release of NE is decreased, this is called what?

Negative feedback system

34

What is the order of the breakdown of NE

Diffuse away from receptor
Reuptake (80%)
MOA and COMT

35

what is MOA

MonoAminoOxydase

36

What is COMT

Catechol-O-Methyl-Transferase

37

What is the synthesis of NE (end with Epi)

Tyrosine
L-Dopa
Dopamine
Norepinephrine
Epinephrine

38

entry of what ion at the nerve terminal is required to release a NT

Calcium

39

what are 2 agents that should be avoided in pts taking MAOi's and why?

indirect acting sympathomimetics (ephedrine)
opioid Meperdine
-B/c both trigger release of NE and may cause HTN crisis

40

what do the receptors do?
Alpha 1

Vasoconstriction
Increased Inotropy

41

what do the receptors do?
Alpha 2

Decreased outflow of SNS
Inhibit NE release
Vasodilation
Decreased Chronotropy

42

what do the receptors do?
Beta 1

Increased Inotropy
Increased Chronotrophy
Increased Dromotropy

43

what do the receptors do?
Beta 2

Increased Inotropy
Increased Chronotropy
Peripheral Vasodilation
Bronchodilation

44

What does Alpha 2 receptors do for pain

stimulation of Alpha-2 receptors in the substantial gelatinosa of the spinal cord promotes analgesia

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