IV anesthetics Flashcards Preview

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Flashcards in IV anesthetics Deck (49)
1

Barbiturates:
name 3 short acting barbs

thiopental (penthothal)
Mexohexital (brevital)
Thiamylal (surital)

2

Barbiturates:
they have many CNS actions but, depression on the _____ undoubtablly contributes to the sedative and hypnotic actions of IV agents

Reticular Activating System (RAS)

3

Barbiturates:Thiopental
has what 2 actions

anticonvulsant
Amnestic

4

Barbiturates:Thiopental
what can occur in small doses

poor analgesic- may increase the reaction to painful stimuli, may be hyperalgesic

5

Barbiturates:Thiopental
does what to respiratory system

depresses it

6

Barbiturates:Thiopental
does what to myocardial contractility

depresses it.- decreases SV, CO, Arterial BP

7

Barbiturates:Thiopental
does what to HR

Increases it

8

Barbiturates:Thiopental
does what to cerebral vascular resistance? what does that mean?

increases CVR
hence decreases cerebral blood flow and ICP

9

Barbiturates:Thiopental
contraintidated in what pts?

porphoria (a neuro dz caused by inadequate porphyrin metabolism)

10

Barbiturates:Thiopental
what would u not use with asthmatics

histamine release

11

Barbiturates: methohexital has excitatory effects. what are they

hiccups
myoclonus

12

Propofol:
what is the 1/2 time to elimination

0.5-1.5 hrs

13

Propofol:
which causes a bigger drop in BP prop or thiopental

prop

14

Propofol:
which has bigger respiratory depression prop or thiopental

prop

15

Propofol:
has antiemetic effects b/c it works where

Chemorecptor trigger zone (CRTZ)

16

Propofol:
does it have antipruritic effects?

yes

17

Propofol:
does it produce analgesia

no

18

Propofol:
does it have anticonvulsant effects

yes

19

Propofol:
does what to CBF and CMRo2

decreases it

20

benzodiazepines:
enhance the action of what receptors

GABA

21

benzodiazepines:
GABA are what?

the brains major inhibitory transmitter

22

benzodiazepines:
name 3 short acting benzos

Diazepam (valium)
Lorazepam (ativan)
Midazolam (versed)

23

benzodiazepines:
do they produce analgesia?

no

24

benzodiazepines:
name 5 CNS effects

Antianxiety
Amnestic
Sedative
Hypnotic
anticonvulsant

25

benzodiazepines:
what CV effects

none unless pt is volume depleted then maybe hypotension

26

benzodiazepines:
does what to brain

cerebral vasoconstriction- lowers CBF and ICP

27

Ketamine:
produces anmesia and profound analgesia by interacting with what receptor

NMDA

28

Ketamine:
Does what to cerebral vasculature

Dilates it
so CBF increases and ICP increases

29

Ketamine:
does what to cerebral metabolism

increases it

30

Ketamine:
does what to eyes and tone

hypertonus and nystagmus

31

Ketamine:
what does it do to CV

Stimulates the SNS which promotes CV enhancement- increased HR, CO, and BP

32

Ketamine:
what pts are good canidates

trauma
elderly

33

Ketamine:
avoid in what pts

CAD
Glaucoma
Increased ICP

34

Ketamine:
emergence can be horrible explain to bad side effects

bad dreams
Hallucinations
n/v

35

Opioids:
why is morphine rarely used for anesthesia

histamine release

36

Opioids:
do what to respiratory system

depress it

37

Opioids:
are they cardiac stable

yep

38

Opioids:
can they produce treacle rigidity

yep

39

Opioids:
what do they do to cerebral blood flow

cerebral vasoconstricor
decreased CBF and ICP

40

Opioids:
why do they cause nausea

stimulate CRTZ

41

Opioids:
how do synthetic opioids cause bradycardia

stimulate the vagal nerve

42

Opioids:
if it caused sphincter of do spasm what can be given to relax it

glucagon 1-2mg

43

Etomidate:
cv effects

minimal

44

Etomidate:
how our it's analgesic and amnestic properties

poor

45

Etomidate:
does what to CBF and ICP

decreases it

46

Etomidate:
what should you look for on injection

pain

47

Etomidate:
what can it cause and how in pts with catecholamine depletion

adrenal cortical suppression
directly depresses cortisol output from the adrenal cortex

48

Etomidate:
does what to the immune system

depresses it

49

the CNS effects after bolus of an IV anesthestic are terminated primarily how

redistribution

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