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Year2 MSK exam 1 > Derm path DSA > Flashcards

Flashcards in Derm path DSA Deck (30)
1

major functions of skin

protective covering
tactile interaction
body temp regulation

2

how does skin fucntion as part of immune system

production of cytokines and defensins
Ag presentation via Langerhans Epidermal Dendritic Cells and possibly dermal dendrocytes

3

organization of skin

epidermis
dermis
subcutis

4

what are the 2 types of dermis

papillary dermis and reticular dermis

5

what are the adnexal structural units of the skin

pilar (hair) units
eccrine units
apocrine units

6

what are the pilar units of skin

pilosebaceous units, arrector pili muscles

7

what are the eccrine units of skin

eccrine glands and ducts

8

what are the apocrine unites of skin

apocrine glands and ducts

9

where is papillary dermis

right beneath the dermal epidermal jucntion

10

what are the stratums of skin in order from most superficial to deep

stratum corneum
stratum lucidum
stratum granulosum
stratum spinosum
stratum basale

11

what is a sebaceous gland

oil gland

12

what is an eccrine gland

sweat gland

13

where are the apocrine glands located

deep dermis and often at junction of reticular dermis and subcutanous tissue

14

what are melanocytes

supply keratinocytes with melanosomes

15

what are the intercellular bridges between squamous cells

desmosomes

16

what makes up the papillary dermis

type I collagen, parallel to surface
some type III and network of elastic fiber
healing by secondary intention
capillaries of superficial plexus (blushing and sunburn)

17

what blistering immune diseases invade BM

bullous pemphigoid
dermatitis herpetiformis
epidermolysis bullosa

18

what is a pacinian corpuscle

encapsulated nerve ending
pressure R
found in deep dermis or hypodermis

19

what is a meissner corpuscle

touch R
confined to dermal papillae
most numerous on hands and feet

20

what type of nerves detect pain and temp

free nerve endings from sympathetic nervous system that controls blood flow and hair movement

21

what makes up the hypodermis

loose and dense CT
adipocytes arranged in lobules
fibroconnective tissue arranged in septae

22

pancreatitis has what type panniculitis

lobular

23

erythema nodosum has what type panniculitis

erythema nodosum

24

hypodermis connects what

reticular dermis with fascia of underlying tissue

25

roles of hypodermis (subcut)

body temp regulation (adipose)
primary depot for fat storage (large energy reserve)
aging most evident in this layer

26

what are wrinkles

basal layer proliferation decreased melanocytes
decrease langerhans
thinning of ground substance

27

what happens to hair follicles with age

decreased hair shaft diameter
decreased number hair follicles (decreased oil production leading to xerosis or dry skin)

28

what is solar elastosis

actinic degeneration of reticular dermis collagen

29

what is telangiectasia

small dilated blood vessels

30

what are the changes in dermis associated with sunburn

increased blood flow
superficial blood vessels show endothelial swelling, perivenular edema, mixed perivascular inflammatory infiltrate