MSK path XI Flashcards Preview

Year2 MSK exam 1 > MSK path XI > Flashcards

Flashcards in MSK path XI Deck (52)
1

ganglions synovial cysts and osteochondral loose bodies form from what

trauma or degenerative processes

2

what is a ganglion

1-1.5 cm cyst usually near joint capsule or tendon sheath
usually around wrist

3

what causes ganglion cyst

cystic or myxoid degeneration of CT
lacks cell lining

4

do ganglion cysts communicate with joint space

no

5

what can cause synovial cyst

herniation of synovium though joint capsule or massive enlargement of bursa

6

what is a baker cyst

synovial cyst in popliteal space in RA

7

synovial lining in synovial vyst

hyperplastic and contain inflammatory cells and fibrin

8

what do ganglion and synovial cysts feel like

soft squishy

9

what is a tenosynovial giant cell tumor

closely related benign neoplasms that develop in synovial lining of joints, tendon sheaths and bursae

10

clinical variants tenosynovial giant cell tumors

diffuse type- pigmented villonodular synovitis)
localized type- giant cell tumor of tendon sheath

11

diffuse tenosynovial giant cell tumors form where

large joints

12

localized type tenosynovial giant cell form where

discrete nodule attached to tendon sheat (commonly the hand)

13

Dx age for tenosynovial giant cell tumors

20-40s

14

color diffuse tenosynovial giant cell tumors

red brown, orange yellow
red brown stripes or folds "tiger stripe"
infiltrate subsynovial tissue

15

localized type tenosynovial giant cell shape

well circumscribed

16

diffuse type tenosynovial giant cell type presents where

knee then hip, ankle, and calcaneocuboid joints

17

Sx diffuse type tenosynovial giant cell

pain, locking and recurrent swelling similar to monoarticular arthritis

18

what limits ROM in joint in tenosynovial giant cell tumors

tumor progression

19

characteristics of localized type tenosynovial giant cell tumor

solitary, slow growing, painless
usually tendon sheaths on wrists and fingers

20

most common mesenchymal neoplasm of hand

localized type tenosynovial giant cell

21

tenosynovial giant cell tumors are Tx how

surgical excision

22

what drugs are used in tenosynovial giant cell tumors

M CSF antagonists b/c block proliferation of giant cells

23

what is soft tissue

non epithelial excluding skeleton, joints, CNS, hematopoietic and lymphoid tissues

24

what are more common benign or malignant soft tissue neoplasms

benign all the way

25

most soft tissue tumors arise where

thigh

26

what is big determinant for soft tissue tumor benign vs malignant

above or below fascial plane

27

what translocation for ewing sarcoma

t11;22

28

soft tissue tumor with eosinphilic spindle cells at 90 angles

smooth muscle type

29

soft tissue tumor with short fascicles of spindle cells like spokes on a wheel

fibrohistiocytic

30

soft tissue tumor arranged in columns, palisading

schwann cell

31

what is characteristic of schwannoma

antoni A and B

32

soft tissue tumor with herringbone

fibrosarcoma

33

soft tissue tumor with mixture fascicles of spindle cells and groups epithelioid cells biphasic

synovial sarcoma

34

important prognostic factors in soft tissue tumors

muscle differentiation, degree of differentiation, size and depth

35

what looks like chinese characters on histo

fibrodysplasia

36

what is a benign tumor of fat and most common soft tissue tumor of adulthood

lipoma

37

what are liposarcomas

50s-60s in deep soft tissues in proximal extremities and retroperitoneum

38

subtypes liposarcomas

well differentiated
myxoid (basophilic extracellular matrix and capillaries, fetal fat looking like stuff)
pleomorphic- sheets anaplastic cells, bizarre nuclei and lots of immature adipocytes

39

what color is the myxoid type liposarcoma

gray

40

what is nodular fascitis

self limited fibroblastic and myofibroblastic proliferation that typically occurs in young adults of upper extremity

41

what is always present in Hx for nodular fascitis

history of trauma

42

5 cm lesion circumscribed, rich cellularity with immature fibroblasts and myofibroblasts in short fascicles
cells vary in shape with conspicuous nucleoli
lots of mitoses
lymphocytes and RBC common

nodular fascitis

43

dupetryns contraction is an example of what

fibromatoses

44

what is pink stuff in fibromatoses

fibrocollagen

45

superficial fibromatosis

infiltrative fibroblastic proliferation
broad fascicles of fibroblasts in long sweeping fascilces with dense collagen

46

what is most comon types of fibromatoses superficial

palmar and plantar

47

what is peyronie disease

penile superficial fibromatoses

48

what are desmoid tumors

deep fibromatosis
recur but no metastasis

49

when do deep fibromatosis present

teens-30s and F>M (weird)

50

types of deep seated fibromatosis

extraabdominal, abdominal and intraabdominal

51

when do you see the extraabdominal deep fibromatosis

W with many babies and C csection scarring

52

gray white firm poorly demarcated mass 1-15 cm
rubbery tough with infiltraiton of muscle nerve and fat
bland fibroblasts in borad sweeping fascicles

fibromatoses