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SEM 2 > FARMACOLOGIE > Flashcards

FARMACOLOGIE Flashcards

(84 cards)

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1
Q

Digoxina

A

Digitalic, tonicardiac in insuf card sau tahiaritmii supraventriculare

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2
Q

Dobutamina

A

beta 1 Adrenomimetic in insuficienta cardiaca

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3
Q

Dopamina

A

beta 1 Adrenomimetic neselectiv in insuficienta cardiaca acuta si soc

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4
Q

Inamrinona si milrinona

A

inhibitoare de fosfodiesteraza cu efect inotrop pozitiv si vasodilatator

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5
Q

Istaroxina

A

Tonicardiac in insuf card

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5
Q

Levosimendan

A

inotrop pozitiv ce se fixeaza de troponina c

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6
Q

Captopril, enalopril, lisinopril

A

Inhibitori ai enzimei de coversie ce reprezinta vasodilatatoare in insuf card

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7
Q

Sartani = losartan, cadesartan, valsartan

A

ANTAGONISTI rec pt angiotensina ce reprezinta efect vasodilatator in insuf card

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8
Q

Nitroglicerina

A

Nitrati oraginici ce reprezinta efect vasodilatator in insuf card

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9
Q

Hidralazina

A

reprezinta efect vasodilatator in insuf card

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10
Q

Prazosin

A

alfa 1 bloc reprezinta efect vasodilatator in insuf card

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11
Q

Nitroprusiat de sodiu

A

reprezinta efect vasodilatator in insuf card

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12
Q

Nesiritida

A

PNA(peptid natriuretic recombinat uman)= acelasi ca BNP ce reprezinta efect vasodilatator in insuf card

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13
Q

Chinidina

A

Clasa 1 de antiaritmice subclasa IA ce deprima moderat viteza de depol sistolica si lungesc perioada PA

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14
Q

Procainamida

A

Clasa 1 de antiaritmice subclasa IA ce deprima moderat viteza de depol sistolica si lungesc perioada PA

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15
Q

Disopiramida

A

Clasa 1 de antiaritmice subclasa IA ce deprima moderat viteza de depol sistolica si lungesc perioada PA

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16
Q

Lidocaina

A

Clasa 1 de antiaritmice subclasa IB ce deprima slab viteza de depol sistolica si scurteaza durata PA

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17
Q

Mexiletina

A

Clasa 1 de antiaritmice subclasa IB ce deprima slab viteza de depol sistolica si scurteaza durata PA

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18
Q

Fenitoina

A

Clasa 1 de antiaritmice subclasa IB ce deprima slab viteza de depol sistolica si scurteaza durata PA —– antiepileptic

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19
Q

Encainida

A

Clasa 1 de antiaritmice subclasa IC ce deprima mult viteza de depol sistolica si nu modifica semnificativ durata PA

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20
Q

Flecainida

A

Clasa 1 de antiaritmice subclasa IC ce deprima mult viteza de depol sistolica si nu modifica semnificativ durata PA

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21
Q

Propafenona

A

Clasa 1 de antiaritmice subclasa IC ce deprima mult viteza de depol sistolica si nu modifica semnificativ durata PA

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22
Q

Amiodora

A

Clasa 3 de antiartmice care prelungesc durata PA ce blocheaza can K - curenti rectificatori de tip Ik

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23
Q

Dronedarona

A

Clasa 3 de antiartmice care prelungesc durata PA
-analog amiodora

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24
Dofetilida
Clasa 3 de antiartmice care prelungesc durata PA - blocant pur al curentului K- ikr
25
Ibutilida
Clasa 3 de antiartmice care prelungesc durata PA -blocant curent k - ikr
26
sotalolul
Clasa 3 de antiartmice care prelungesc durata PA = beta bloc
27
Bretiliul
Clasa 3 de antiartmice care prelungesc durata PA - elibereaza catecolaminele in fanta sinaptica si deci nVu mai este utilizat
28
Verapamil
Clasa 4 de antiartmice care blocheaza can de Ca cu structura fenilachilaminica NUMAI NU DIHIDROPIRIDINICA - caci nu au ef asupra cordului
29
Diltiazemul
Clasa 4 de antiartmice care blocheaza can de Ca cu structura benzotiazepinica
30
ACH
antiaritmic ce deprima cordul
31
Endrofoniul
antiaritmic - anticolinesterazic reversibil cu durata mica de actiune ce creste disponibilul de Ach in fanta sinaptica
32
Adenozina
antiaritmic ce actioneaza pe rec adenozinic cuplat cu prot G ce deschide can de K dependente de Ach
33
Digitalicile
antiaritmic la fel ca si efect tonicardiac
34
Nitropursiatul de sodiu
Nitratii organici, au efect vasodilatator si antianginos
35
Nitroglicerina
Nitratii organici, au efect vasodilatator si antianginos
36
Milsodomina
Asemanatoare-Nitratii organici, au efect vasodilatator si antianginos
37
Izosorbid dinitrat
Nitratii organici, au efect vasodilatator si antianginos
38
Nifedipina
bloc de can de CA- dihidropiride cu efect antianginos ce produce vasodil coronariana si arteriolara
39
Amlodipina
bloc de can de CA- dihidropiride cu efect antianginos ce produce vasodil coronariana si arteriolara
40
Verapamil
Bloc de can de Ca = fenilalchilamine cu efect antianginos ce deprima nod sinoatrial si A-V + efect vasodilatator
41
Diltiazemul
bloc de can de CA- benzotiazepine cu efect antianginos ce produce vasodil mai activa
42
Nicorandilul
antianginos ce e activator can de K cu actiune vasodil de tip nitrat
43
Trimetazina
antianginos ce amelioreaza metabolismul cel miocardice prin inhibarea oxid AG
44
Ranolazina
antianginos ce scade contractilitatea miocardica
45
Ivabradina
antianginos ce scade frecventa cardiaca prin inhibarea directa a can ionice de tip funny
46
Clonidina
antihipertensiv ce scade controlul simpatic ce are efect simpatomimetic alfa 2
47
Metildopa
antihipertensiv ce scade controlul simpatic = analog dopa
48
Moxonidina
antihipertensiv ce scade controlul simpatic = actioneaza pe rec imidozolinic la niv bulbului ce scade TA si efecte slabe alfa 2
49
Rilmenidina
antihipertensiv ce scade controlul simpatic = actioneaza pe rec imidazol
50
Guanabenzul
antihipertensiv ce scade controlul simpatic ce e asemanator clonidinei
51
Trimetafan
Antihipertensiv ce scade controlul simpatic = ce e ganglioplegic ce blocheaza rec din gangl veg simpatici si parasimpatici
52
Guanetidina
Antihipertensiv ce scade controlul simpatic =
53
Rezerpina
antihipertensiv ce scade controlul simpatic = impiedica recaptarea noradrenalinei
54
Fentolamina
antihipertensiv ce scad controlul simpatic = bloc neselectiv alfa
55
Prozasin, doxazosin, terazosin
antihipertensiv ce scad controlul simpatic = alfa 1 bloc selectiv
56
Urapidil
antihipertensiv ce scad controlul simpatic = alfa 1 bloc dar si agonist slab alfa 2 , beta 1 si seroton
57
Hidralazinele
antihipertensivele ce sunt vasodil directe
58
Minoxidil
antihipertensivele ce sunt vasodil directe = deschid can de K la niv muscular vascular
59
Diazoxidul
antihipertensivele ce sunt vasodil directe = mecanism de actiune prin can de K
60
Fenoldopamul
agonist pe rec D1 = antihipertensivele ce sunt vasodil directe
61
Dihidropiridinele
antihipertensive mai ales cu actiune la niv vaselor
62
Fenilalchilaminele
antihipertensive cu efect la nivelul cordului
63
Benzotiazepinele
antihipertensive cu efect intermediar intre cord si vase
64
Saralazina
antihipertensiv cu ef ANTAGONIST LA NIV REC ANGIOTENSINEI
65
Alikirenul
antihipertensiv cu ef ANTAGONIST LA NIV REC ANGIOTENSINEI
66
Hidroclorotiazida
antihipertensiv diuretic tiazidic ce inhiba reabs sarii fara apa la niv tub contort distal - inhiband mec simport de transport al grupelor de 2 ion na si cl
67
Indapamida
antihipertensiv diuretic fals tiazidic ce inhiba reabs sarii fara apa la niv tub contort distal - inhiband mec simport de transport al grupelor de 2 ion na si cl
68
Furosemid
antihipertensiv diuretic de ansa ce inhiba reabs sarii fara apa la nivelul portiunii ingrosate a ansei henle ascd
69
Bumetanidul
diuretic de ansa ce inhiba reabs sarii fara apa la nivelul portiunii ingrosate a ansei henle ascd
70
Torsemidul, ac etacrimic
diuretic de ansa ce inhiba reabs sarii fara apa la nivelul portiunii ingrosate a ansei henle ascd
71
Butizida
diuretic tiazidic ce inhiba reabs sarii fara apa la niv tub contort distal - inhiband mec simport de transport al grupelor de 2 ion na si cl
72
Ciclotiazida si politiazida
diuretic tiazidic ce inhiba reabs sarii fara apa la niv tub contort distal - inhiband mec simport de transport al grupelor de 2 ion na si cl
73
Clortalidona , clopamida
diuretic fals tiazidic ce inhiba reabs sarii fara apa la niv tub contort distal - inhiband mec simport de transport al grupelor de 2 ion na si cl
74
75
Spironolactona
diuretic antialdosteronic
76
Eplerenona
diuretic antialdosteronic ce blocheaza rec aldosteronici
77
Canrenoatul de K
diuretic antialdosteronic
78
Acetazolamida
diuretic inhibitor ale anhidrazei carbonice
79
Manitol
diuretic osmotic = substante coloid osmotice ce nu transverseaza peretii capilarelor sg in general dar filtreaza glomerular, nu se absorb tubular. si se elimina prin urina cu echivalentul osmotic de apa
80
Uree sau izosorbidul
diuretic osmotic = substante coloid osmotice ce nu transverseaza peretii capilarelor sg in general dar filtreaza glomerular, nu se absorb tubular. si se elimina prin urina cu echivalentul osmotic de apa
81
Rolofilina
puternic bloc al rec adenozinici tip A1 = fiuretic alt
82
Tolvaptanul
blocheaza selectiv rec vasopresinergici de tip V2 = diuretic alt
83
Conivaptanul
blocheaza rec v2 si V1a vasodil = diuretic alt

SEM 2 (16 decks)

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