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Flashcards in female reproductive Deck (41):
1

estrogen is made in:

corpus luteum

2

estrogen cause proliferation of:

stroma, blood vessels, endometrium

3

function of progesterone:

store food in granular cells

4

commonest causes of vaginal bleeding

hormonal disorders, genital neoplasia

5

types of genital neoplasia?

fibroids, endometrial disease, cervical disease

6

most common benign tumour of myometrium

fibroids

7

___% women have uterine fibroids

20

8

what is DUB?

dysfunctional uterine bleeding caused by absence of well-defined organic lesion in the uterus

9

DUB characterized by:

anovulation

10

endometrial hyerplasia caused by:

xs of estrogen (continuous proliferative phase)-->anovulatory cycles around menopause, exogenous estrogen, PCOS

11

types of endometrial hyperplasia:

simple, complex, complex with atypia

12

two types endometrial carcinoma

endometrioid, serous

13

risk factors of endometrioid?

obesity, diabetes, hypertension, infertility, age 55-65

14

risk factors for serous?

>70 yrs age

15

serous has a good or bad prognosis?

Bad, it's high grade carcinoma

16

20% of malignant tumours of female repro tract

carcinoma of cervix

17

early detection of cervical cancer by:

PAP smear

18

most common cervical cancer-causing HPV are"

type 16 and 18

19

low grade HPV are types:

6 and 11

20

cervical cancer arises in ___ zone

transformation

21

cervical cancer involves __ cells

squamous

22

what is transformation zone?

point where squamous epithelium becomes glandular in cervix

23

early symptoms of cervical cancer

post-coital bleeding, vaginal discharge

24

pelvic inflammatory disease involves:

endometritis, cervicitis, salpingitis, oophoritis

25

is vulvovaginitis usually ascending or descending?

ascending (sex)

26

chlamydia presents clinically as:

vaginal discharge, ab pain, infertile

27

common infections:

herpes (blisters), HPV (warts), infectious vaginitis, chlamydia, gonorrhea, symphilis

28

local symps of gonorrhea

urethritis, proctitis, PID, septicemia, arthritis

29

where is milk made?

acinar duct

30

____ part of acinar is where disease starts

terminal

31

two types of fibrocystic change

nonproliferative, proliferative

32

common benign tumour in young femals, 2-5cm

fibroadenoma

33

fibroadenoma maybe caused by?

exaggerated response of breast tissue to sex hormones (estrogen)

34

incidence of fibroadenoma is :

1 in 10 women

35

most common cancer in women

breast cancer (1/10 women)

36

risk factors for breast cancer

hormonal (E2 exposure, nulliparous women, anti-estrogen drugs), race (Jewish), reproductive history, premalignant fibrocystic changes (papillomatosis)

37

what cause breast cancer?

atrophy

38

two types of breast cancer?

infiltrating duct, lobular

39

infiltrating duct characterized by a ____ tumour and ___ of nipple

firm, gritty; retraction

40

breast cancer detected by:

self exam, physician palpation, mammography

41

diagnosis of breast cancer:

fine needle aspiration, surgical biopsy