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Flashcards in cell pathology Deck (37):
1

study of tissue diseases

histopathology

2

essential part of most living cells w/ DNA, RNA, proteins

nucleus

3

in resting cells, components in nucleus aggregate as ____ and in dividing cells, condense into ___

chromatin; chromosomes

4

all human cells except ___ need nucleus

platelets and RBC

5

^ N:C ratio found in:

tumour cells, embryonic cells (undifferentiated)

6

cytoplasmic ground substance

hyaloplasm

7

primary site of protein synth

RER

8

catabolism of drugs/hormones/nutrients and synth of steroids

SER

9

_____- are formed in golgi

glyco/lipoproteins

10

primary lysosomes have acid ____

hydrolases

11

secondary lysosomes (fusion with foreign vesicles) called

heterophagosomes

12

plasma mem arranged in ____ bilayer

polarized complex

13

paracrine stim by:

biogenic amines and neuropeptide hormones

14

endocrine stim by:

hormones released into blood

15

inside enviro of cell

internal milieu

16

ex. of oligominerals

zinc, copper, selenium, magnesium

17

what are essential minerals?

iron, chloride, potassium, calcium

18

reversible cell injury characterized by:

swollen mito,, switch to anaerobic metabolism, degranulated RER

19

reversible cell injury may be produced by:

expose to toxins, hypoxia

20

irreversible cell injury characterized by:

nuclear changes-->ultrastructural

21

3 types nuclear damage

pyknosis (dense chromatin), karyorrhexis (fragmentation), karyolysis (dissolution)

22

causes of cell injury

hypoxia, toxins, microbe pathogens, endogenous mediators, gene/metabolic disturbances

23

examples of hypoxia

myocardial infarction, choking

24

Cells change to another type

Metaplasia

25

Usually due to chronic irritation or hormone stim

Hyperplasia

26

3 types of necrosis

Coagulative, liquifactive, caseous

27

Type of necrosis in TB

Caseous (cheesy)

28

Secondary Infection of necrotic tissue

Gangrène

29

decrease in size of cell

atrophy

30

hyperplasia caused by :

hormonal stim, chronic irritation

31

accumulation of coal particles

anthracosis

32

accumulation of blood-derived brown pigment

hemosiderosis

33

exogenously induced death

necrosis

34

programmed cell death

apoptosis

35

death of cells after death of organism

autolysis

36

most common type of necrosis marked by rapid inactivation of hydrolytic enzymes?

coagulative

37

liquefactive necrosis common in_____

brain