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Flashcards in Pathology of Neuroplasia Deck (29)
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1

cancer is ___ disease

genetic/molecular

2

non-specific swelling

tumour

3

new growth

neoplasm

4

bumps that aren't cancer

deep tissue damage, lymph nodes, cysts

5

abnormal/different location of normal tissues

heterotopia

6

grow slow, resemble organ of origin, don't spread distant

benign tumour

7

grow fast and may not resemble organ of origin, metastasis, kill

malignant tumour

8

general 3 kinds of names for malignant tumor

carcinoma, sarcoma, blastoma

9

refers to abnormal features of nuclei in neoplastic cells

anaplasia

10

side effects of chemotherapy

hair loss, diarrhea, bone marrow suppression (infection, hemorrhage)

11

altered architecture and cell abnormalities confined to within the basement mem

dysplasia

12

some treatments for cancer

surgery, radiation, chemotherapy, experimental (immunotherapy)

13

treatment used to shrink tumour size

radiation

14

therapy that destroys rapidly dividing cells

chemotherapy

15

pathologic space occupying lesions that can evolve into frank neoplastic process

preneoplastic lesions

16

what is a transformed cell?

irreversibly committed to cancerous

17

takes __ divisions to reach clinical detection (from transformed cell) and ___ divisions from there to fatal tumour

30; 10

18

what is the fastest growing human tumour?

burkitt's lymphoma

19

what is max diffusion distance?

1-2 mm

20

what are clinical features of neoplasm?

local mass lesions, metastases, systemic effects on host, incidental detection

21

examples of systemic effects on host?

lack of appetite and lost weight, sweating, fever, cachexia

22

what are paraneoplastic syndromes?

inappropriate expression of genes that are normally silent in organ of cancer

23

ulcers are associated with:

diabetes, cancer, yellow pus patches (infections)

24

what is a sign that the ulcer is cancerous?

everted edges

25

hypercoagulable state is associated with:

acute myeloid leukemia

26

clinical features are ___ mediated

cytokine

27

what are 7 warning signs?

change in bowel or bladder, a sore that doesn't heal, unusual bleeding/discharge, thickening of lump in breast, indigestion/difficulty swallow, obvious change in wart/mole, nagging cough

28

benign tumors generally disignated by suffix:

"oma"

29

malignant tumours generally 3 kinds of names:

carcinoma (epithelial), sarcoma (mesenchymal), blastoma (fetal)