What is fertilisation?
The fusion of the male nuclei and female gametes that results in the production of new offspring.
What is needed for fertilisation to occur?
Male sperm need to be brought into contact with a female ovum.
What is insemination?
When an erect penis releases semen into the vagina through ejaculation during sex.
How does an erection happen?
Results from blood rushing into the spaces of the penis’ erectile tissue initiated by sexual excitation
What is ejaculation?
Muscular contractions that propel semen from the penis.
What is semen?
The liquid that nourishes and aids the transport of sperm - aka seminal fluid
What does semen contain?
Secretions of seminal vesicles, bulbo-urethral glands, and prostate gland
What is the function of semen?
What does the vagina do to allow for easy entry of the penis?
Copious secretions of mucus by glands located around the cervix and in the vaginal opening region lubricate epithelial lining.
What happens to sperm once within the vagina?
The sperm travel through the cervix and the uterus body into the uterine tube. They reach the upper portions within a few minutes
What helps sperm through the female reproduction tract?
Muscular contractions of the uterus
What helps transport ova towards the uterus after ovulation?
Muscular contractions of the uterine tube, together with the beating action of cilia
How many sperm reach the uterine tubes
Only a few thousand reach the uterine tube
What is sperm mortality?
The death rate of sperm - high
Where does fertilisation occur?
In the uterine tubes when the ovum is about 1/3 of the way down the tube
What are the two layers of the secondary oocyte?
What is the corona radiata?
Consists of follicle cells held together by cementing materials that contain acid.
What is the zona pellucida?
A glycoprotein matrix surrounding the plasma membrane of the oocyte
What is the function of the enzyme in the outer surface of the acrosome on the sperm’s head?
Capable of breaking down the acid in the cementing material that holds the cells of the corona radiata together
Why are a large number of sperm required if fertilisation is to occur?
When several thousand sperm surround oocyte there is enough enzyme to loosen corona cells, allowing 1 sperm to penetrate corona radiata.
What is the first step of fertilisation?
Hundreds of sperm attracted to corona radiata begin to break through barrier of granulosa cells and approach zona pellucida
What is the second step of fertilisation?
Contact with zona pellucida triggers acrosome reaction, causing sperm secrete digestive enzymes that break down glycoprotein membrane of zona pellucida and help to expose oocytes plasma membrane
What is the third step of fertilisation?
A single sperm succeeds in burrowing through corona radiate/zona pellucida and making contact with oocyte’s plasma membrane.
What is the fourth step of fertilisation?
Sperm’s plasma membrane fuses with that of oocyte and sperm releases its nucleus into cytoplasm of oocyte.