What are stem cells?
Cells that have the ability to produce different types of body cells.
How are stem cells different to other cells?
Because they are not specialised for any particular role and are capable of repeated division by mitosis
How can stem cells divide by mitosis?
Through simple mitosis, a stem cell can make exact copies of itself indefinitely.
Once specialised, stem cells have limited capacity to reproduce themselves.
What is stem cell proliferation?
When specialised cells are unable to divide.
Therefore, they must be new stem cells or cells that differentiate to form specialised cells.
How can stem cells be classified?
Stem cells can be classified based on:
1. Where they originate (embryonic, adult stem cells or cord blood)
What is differentiation?
The process by which cells become specialised so they can perform particular functions – e.g. stomach cells that secrete enzymes
What is potency?
Refers to the potential capacity of a stem cell to differentiate into different specialised cell types
What is a totipotent stem cell?
Have the potential to create any type of cell necessary for embryonic development, including the embryo and all membranes associated with embryonic development that will surround/support/nourish it.
What is an example of a totipotent?
The early embryo before the formation of the inner cell mass.
What is a pluripotent stem cell?
Have the potential of developing into any of the cell types found in the adult.
What is an example of a pluripotent?
The inner cell mass.
What is a multipotent stem cell?
Have the potential of developing into a few cell types with a specific function – usually those found in the organ they’re derived.
What is an example of a multipotent?
Blood stem cells which give rise to red blood cells, white blood cells and platelets.