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Flashcards in fong 2 Deck (27):
1

what is the basic functional unit of the kidney?

nephron

2

functions of the nephron?

-filtration
-reabsorption
-secretion

3

loss of functional nephron units is a consequence of what disease?

Polycystic Kidney Disease (humans and cats)

4

what S segments are part of the proximal convoluted tubules?

S1 and S2

5

what S segments are part of the proximal straight tubule?

S3

6

how does the glomerulus discriminate between solutes?

-size
-charge
-shape

7

the bulk of filtered solutes is REABSORBED where?

the proximal tubule

8

does the proximal tubule secrete select substances?

yes

9

what kind of transport is in the PT?

-Na+ coupled transport
-isotonic

10

which PT segment has more mitochondria (S1 or S3)?

S1

11

what are the two types of nephrons?

-cortical nephrons
-juxtamedullary nephrons

12

what are two characteristics of cortical nephrons?

-short-looped
-renal corpuscles CLOSE to kidney surface

13

what are two characteristics of juxtamedullary nephrons?

-long-looped
-renal corpuscles DEEPER within kidney

14

what type of nephron is an important concentrating mechanism?

juxtamedullary nephrons

15

T/F: concentrating ability is loosely related to the proportion of long-looped nephrons.

True

16

what are the H2O and NaCl permeabilities of the thin descending limb of the loop of henle?

-high H2O permeability
-no NaCl permeability

17

what are the H2O and NaCl permeabilities of the thin ascending limb of the loop of henle?

-high NaCl permeability
-no H2O permeability

18

what are the H2O and NaCl permeabilities of the thick descending limb of the loop of henle?

-high ACTIVE transport of NaCl (requires ATP!)
-no H2O permeability

19

the selective permeabilities of the loop segments promotes establishment and maintenance of ______ that is a necessary concentrating mechanism.

medullary hypertonicity

20

tubular fluid in the distal tubule is what?

hypotonic

21

what do macula densa cells sense?

salt load

22

what provides tubuloglomerular feedback?

the juxtaglomerular (JG) apparatus

23

the tubuloglomerular feedback enables balance between what?

renal blood flow and glomerular filtration

24

what is absorbed in the distal convoluted tubule?

Na, Ca, Cl

25

what are the functions of the collecting duct?

-hormone-sensitivity
-fine-tuning salt, H2O and acid-base balance

26

what are the 3 parts of the collecting duct?

-cortical
-outer medullary
-inner medullary

27

what is the cell population in the collecting duct?

heterogenous cell population