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Flashcards in fong VII Deck (12):
1

what contributes to the osmotic gradient?

NaCl and urea

2

what causes the generation of medullary interstitial hypertonicity ?

active NaCl absorption by TALH ( role of urea recycling)

3

what causes the generation of medullarry interstitial hypertonicity?

differential NaCl and H2O permeabilities of all segments of henle's loop

4

what is absorbed in the medullary collecting duct?

-REGULATED permeability to both Na+ and water
-urea is reabsorbed

5

what keeps the gradient intact?

countercurrent exchange

6

what does feeling does ADH stimulate?

thirst

7

ADH release is impaired in what disease?

CENTRAL DI

8

CENTRAL DI characteristics

-ADH signaling is impaired
-defect is at the SOURCE

9

NEPHROGENIC DI characteristics

-ADH signaling is impaired
-defect is the TARGET

10

in an ADH response test, which form of DI should the administration of ADH increase water absorption?

CENTRAL CI

11

Na+ absorption by CD principle cells is enhanced by what?

aldosterone

12

what does atrial natriuretic peptide inhibit?

Na+ absorption in the CD and it also inhibits angiotensin II (leading to vascular relaxation) and aldosterone production by the adrenal gland