G-protein linked 2nd messengers Flashcards Preview

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Flashcards in G-protein linked 2nd messengers Deck (13):
1

alpha1

q

sympathetic

increases vascular smooth muscle contraction, increases pupillary dilator muscle contraction (mydriasis), increases intestinal and bladder sphincter muscle contraction

2

alpha2

i

sympathetic

decreases sympathetic outflow, decreases insulin release, decreases lipolysis, increases platelet aggregation

3

beta1

s

sympathetic

increases heart rate, increases contractility, increases renin release, increases lipolysis

4

beta2

s

sympathetic

vasodilation, bronchodilation, increases heart rate, increases contractility, increases lipolysis, increases insulin release, decreases uterine tone (tocolysis), ciliary muscle relaxation, increases aqueous humor production

5

M1

q

parasympathetic

CNS, enteric nervous system

6

M2

i

parasympathetic

decreases heart rate and contractility of atria

7

M3

q

parasympathetic

increases exocrine gland secretions, increases gut peristalsis, increases bladder contraction, bronchoconstriction, increases pupillary sphincter muscle contraction (miosis), ciliary muscle contraction (accomodation)

8

D1

s

relaxes renal vascular smooth muscle

9

D2

i

modulates transmitter release, especially in brain

10

H1

q

increases nasal and bronchial mucus production, contraction of bronchioles, pruritus and pain

11

H2

s

increases gastric acid secretion

12

V1

q

increases vascular smooth muscle contraction

13

V2

s

increases H2O permeability and reabsorption in the collecting tubules of the kidney

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