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Flashcards in gold usmle: CNS pharm Deck (62)
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31

Tramadol

Ambulatory txt for mod. to severe pain

32

Naloxone

Txt opioid OD. Reverses respiratory depression

33

Pentazocine

Part κ(+) & part μ(-)

34

Butorphenol

Part κ(+) & part μ(-)

35

Nalbuphene

Part κ(+) & part μ(-)

36

↓ GABA

↓ seizure focus= Barbs & BDZs

37

↓ Fast Na Ch.

↓ electrical activity spread = Phenytoin & Carbamazepine

38

Methoxyflurane

Can be nephrotoxic. Needs low MAC for anesthetic induction.

39

Enflurane

Can cause tonic/clonic muscle spasms

40

Isoflurane

Can cause bronchospasm

41

Halothane

Can cause ventricular extrasystoles & Malignant hyperthermia & Hepatitis

42

Nitric Oxide

No effect on HR. Needs high MAC for anesthetic induction.

43

Thiopental

Short acting Barb.

44

Ketamine

Dissociative anesthetic

45

Droperidol

Can be used in combo w/ Fentanyl for neuroleptoanalgesic effect
52. Neuroleptic tranquilizer. Has mild alpha block

46

Fentanyl

Can be used on combo w/ Droperidol for neuroleptoanalgesic effect
54. Used transdermally for chronic pain

47

Midazolam

Pre anesthetic. Induces amnesia

48

Primidone

Biotransformed to Phenobarb.

49

C & A delta Fibers

First fibers to be blocked w/ anesthesia

50

Esters

Procaine, Tetracaine, Benzocaine
59. Broken down and make PABA (allergen)

51

Amides

Lidocaine, Mepivaciane, Bupivaciane, Etidocaine= “i” before “caine” always an amide
61. Metabolized in the liver

52

Amphetamine

DA reuptake (-)’r. MAOI. Parkinson’s txt

53

Bromocriptine

D2(+). Used w/ L-Dopa for “on-off” phenomenon of Parkinson’s

54

Benztropine

Ant M w/ some DA reuptake (-). Parkinson’s txt

55

Amantidine

↓ DA reuptake. Can cause livido reticularis= skin mottling.

56

Diphenhydramine

Txt early Parkinson’s stages

57

Pergolide

> Effective & longer acting than Bromocriptine

58

Ethosuximide

DOC for Absence seizures

59

Tranylcypromine

. MAOI = antidepressant
reversible inhibitor

60

SSRI & MAOI

Fatal combo, especially seen with the use of Paroxetine or Fluoxetine (SSRIs) and Tranylcypromine (MAOI)