Flashcards in Handout 3 Deck (19):
the number of cells needed to kill half of the animals in a test group?
hylaruonidase, collagenase and fibrinolyse help with what virulence factor?
part of bacteria- the LPS in gram negative bacteria
exotoxins are secretes- like AB toxins etc.
toxin that affects the intestinal mucosa?
what is a PAI? pathogenicity island?
this is when virulence factors are grouped together- often on a plasmid
increase their ability to cause disease obviously
what do the bacteria of a biofilm have?
quorum sensing- colony of bacteria with a biofilm.
we see this in the mouth
work against infection by destroying or inhibiting microorganisms on skin or mucus membranes
kill most, not all microbes – NOT given to patients except alcohol on skin
used to kill all microbial forms, even spores
what is soap an example of?
antiseptic. uses detergent to remove oils
what is chlorohexidene example of?
disrupts the bacterial cell membrane. residual activity
what does fluoride inhibit?
enolase. this is an enzyme that is found in organisms that use fermentation
hydrogen peroxide is a _____ agent
how does listerine work?
phenolic compounds disruptiong enzymes/denatures proteins
removes all life forms including spores – indicator organism is a spore forming bacteria – Bacillus or Clostridium
what is the indicator organism in disinfection?
what level of disinfectant?
floors, countertops (quaternary ammonium)
what level disinfectant?
semi-critical instruments – does not remove spores (alcohol + something, phenolic compounds, iodophors, bleach)
what are semi critical instruments?