Handout 3 Flashcards Preview

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Flashcards in Handout 3 Deck (19):
1

the number of cells needed to kill half of the animals in a test group?

LD50

2

hylaruonidase, collagenase and fibrinolyse help with what virulence factor?

invasion

3

part of bacteria- the LPS in gram negative bacteria

endotoxins
exotoxins are secretes- like AB toxins etc.

4

toxin that affects the intestinal mucosa?

enterotoxin

5

what is a PAI? pathogenicity island?

this is when virulence factors are grouped together- often on a plasmid
increase their ability to cause disease obviously

6

what do the bacteria of a biofilm have?

quorum sensing- colony of bacteria with a biofilm.
we see this in the mouth

7

work against infection by destroying or inhibiting microorganisms on skin or mucus membranes

antiseptics

8

kill most, not all microbes – NOT given to patients except alcohol on skin

disinfectants

9

used to kill all microbial forms, even spores

sterilants

10

what is soap an example of?

antiseptic. uses detergent to remove oils

11

what is chlorohexidene example of?

antiseptic agent.
disrupts the bacterial cell membrane. residual activity

12

what does fluoride inhibit?

enolase. this is an enzyme that is found in organisms that use fermentation

13

hydrogen peroxide is a _____ agent

oxidizing

14

how does listerine work?

phenolic compounds disruptiong enzymes/denatures proteins

15

removes all life forms including spores – indicator organism is a spore forming bacteria – Bacillus or Clostridium

sterilization

16

what is the indicator organism in disinfection?

mycobacterium tuberculosis!!!!

17

what level of disinfectant?
floors, countertops (quaternary ammonium)

low level

18

what level disinfectant?
semi-critical instruments – does not remove spores (alcohol + something, phenolic compounds, iodophors, bleach)

intermediate level.
what are semi critical instruments?

19

what level of disinfectant?nearing sterilization – for equipment you can’t sterilize (bleach, ethylene oxide 2% gluteraldehyde, peroxide)

high level.