Flashcards in Handout15 Deck (13):
what are the bacteria that are normal flora in the mouth and found in plaque biofilms?
makes a sticky surface for other bugs?
*dexter is a sticky kind of guy*
used by bacteria to store energy?
*glucan glue can give you energy!* kid's that eat glue
additional storage forms made by bugs-
fructans/levans. when these get broken down the plaque gets more acidic.
what are the examplsof polysaccharides that bugs make? they hydrolyze the SUCROSE and make these
dextrans, glucans, fructans/levans.
how do bacteria stick to the tooth or plaque to cause caries?
MUST have bugs to get perio disease.
they stick by CA2+ ions to make a bridge between the enamel and pellicle and bug
OR more likely bacteria use their fimbrae, pill, or flawless to bind to the glyocproteins (salivary) or the pellicle
what is a biofilm?
biofilm is defined as a complex, functional community of one or more species of microbes, encased in an exopolysaccharide matrix and attached to one another or to a solid surface
what is the pioneer group of bacteria made of?
gram + cocci and rods
what's next after the pioneer group?
then you have the gram - cocci and rods (because they're more anaerobic)
what are the last colonizers of the biofilm?
fusobacterium, spirillum, Spirochetes
they're most anaerobic!
what are the 3 things quorum sensing does for communication?
1) Control genes related to extracellular polysaccharide production (remember, that's what the bacteria make out of the sucrose)
2) Reduce metabolism (for bacteria at the bottom of the matrix)
3) Control production of virulent factors, including drug-destroying genes
*so they have to do with genes and metabolism*
what are the free living organisms called? what are most human infections caused by?
most human infections are from the organisms encased in biofirlms- called sessile.
free living are the planktonic.